摘要
目的探讨移植2枚或3枚胚胎与临床结局的关系,为高龄女性胚胎移植数的选择提供依据。方法对80个卵裂期胚胎新鲜移植周期进行回顾性分析,根据移植胚胎数将这些周期分组,并对各组的临床妊娠率、种植率、多胎妊娠率及活产率进行比较。结果对于年龄≥38岁的女性,当可利用胚胎数≥3枚时,移植2枚胚胎与移植3枚胚胎能够获得相似的临床妊娠率及活产率。这一趋势与所移植的8-细胞胚胎数无关。结论高龄女性新鲜卵裂期胚胎移植数目不宜超过2枚。
Objective To explore the relationship between clinical outcomes and embryo transfer number,and to provide some proposals for transfer selection of elderly patients.Methods Data from 80 fresh transfer cycles with cleavagestage embryos were analyzed.Cycles were divided into several groups according to transfer number.Clinical pregnancy rate,implantation rate,multiple pregnancy rate and live birth rate were compared.Results To women no younger than 38 years old,when available embryo number was larger than two,similar clinical outcomes could be achieved by transferring two and three embryos.This trend was independent of the number of transferred 8-cell embryos.Conclusion The number of fresh cleavage-stage embryos transfer should not exceed two in elderly women.
作者
付磊
周雯慧
FU Lei;ZHOU Wen-hui(Medical Center for Human Reproduction,Beijing Chao-Yang Hospital,Capital Medical University,Beijing 100020,China)
出处
《解剖学报》
CAS
CSCD
北大核心
2021年第1期113-117,共5页
Acta Anatomica Sinica
基金
国家自然科学基金(81501323)
北京市医管局临床技术创新项目(XMLX201810)
北京朝阳医院朝阳新星计划(CYXX-2017-19)。
关键词
人类辅助生殖
卵裂期胚胎移植
移植胚胎数
临床结局
体外受精
高龄女性
Human assisted reproduction
Cleavage-stage embryo transfer
Transfer number
Clinical outcome
In vitro fertilization
Elderly woman
