摘要
目的研究超声检查对桥本甲状腺炎(HT)伴发结节良、恶性的鉴别诊断价值。方法回顾性分析2019年3至7月100例HT伴甲状腺结节患者,所有患者均在术前接受超声检查并依据结节大小(10 mm)及纵横比(A/T)值(1.0)为诊断标准,分为良性结节组和恶性结节组。以病理结果为诊断金标准,采用χ^(2)检验比较两组患者超声诊断效能。结果良性组患者的甲状腺结节横径、纵径均大于恶性组,而A/T值低于恶性组,差异有统计学意义(t值分别为18.541、13.220、9.678,P值均<0.05);超声检查诊断HT患者合并恶性结节38例、病理诊断40例。超声检查诊断HT患者合并恶性结节的敏感度95.0%,特异度100.0%,阳性预测值100.0%,阴性预测值96.8%。结论超声检查可有效诊断HT及鉴别诊断伴发结节性质。
Objective To study the value of ultrasonography in the differential diagnosis of Hashimoto thyroiditis(HT) with benign and malignant nodules. Methods In a retrospective analysis from March to July 2019,100 patients with HT accompanying thyroid nodules received preoperative ultrasonography. Based on the diagnostic criteria, nodule size(10 mm), and aspect ratio(A/T) value(1.0), these patients were divided into benign nodules group and malignant nodules group. Based on the gold diagnostic standard, pathological results, for diagnosis, χ^(2) tests were used to compare the diagnostic efficacy of ultrasonography in the two groups. Results The transverse and longitudinal diameters of the benign group’s thyroid nodules were larger than those in the malignant group, while the A/T value was lower than that of the malignant group.The difference was statistically significant(t=18.541,13.220,9.678;all P < 0.05);38 cases of HT patients with malignant nodules were diagnosed by ultrasonography, and 40 cases were diagnosed by pathology. The sensitivity of ultrasonography to diagnose HT patients with malignant nodules was 95.0%, specificity was 100.0%, positive predictive value was 100.0%, and the negative predictive value was 96.8%. Conclusion Ultrasonography can effectively diagnose HT and differentially diagnose if the concomitant nodules are benign or malignant.
作者
郑磊
荆红艳
刘丽红
王廉一
ZHENG Lei;JING Hongyan;LIU Lihong;WANG Lianyi(Department of Ultrasonography,the First Affiliated Hospital of Tsinghua University,Beijing 100016,China;Operating Room of the First Affiliated Hospital of Tsinghua University,Beijing 100016,China)
出处
《中国研究型医院》
2021年第2期39-42,共4页
Chinese Research Hospitals
关键词
超声检查
桥本病
甲状腺炎
自身免疫性
甲状腺结节
诊断
鉴别
Ultrasonography
Hashimoto disease
Thyroiditis,autoimmune
Thyroid nodule
Diagnosis,differential
