摘要
目的探讨甲状腺结节合并桥本氏甲状腺炎（Hashimoto’sthyroiditis，HT）与甲状腺癌风险之间的关系。方法回顾分析2010年1月至2017年7月于天津医科大学第二医院接受甲状腺结节切除手术的患者1212例，根据术后病理学结果进行分组比较，对比分析合并桥本氏甲状腺炎的甲状腺结节中甲状腺癌的发生率。结果良性结节843例，其中合并桥本氏甲状腺炎患者占15．3％：恶性结节369例，其中合并桥本氏甲状腺炎患者占10．8％。169例甲状腺结节合并桥本氏甲状腺炎患者中，甲状腺乳头状癌占23．7％。未合并桥本氏甲状腺炎的患者中，甲状腺乳头状癌占30.3％，2者比较差异无统计学意义（Х^2=3．08．P〉0．05）．说明甲状腺结节合并桥本氏甲状腺炎不增加甲状腺乳头状癌的发生风险。结论甲状腺结节合并桥本氏甲状腺炎时并不增加患甲状腺癌的风险。
Objective To evaluate the relationship between thyroid nodules combined with Hashimoto＇s thyroiditis（HT） and the risk of thyroid cancer. Methods This retrospective study included 1212 patients undergoing thyroideetomy in the Second Hospital of Tianjin Medical University from Jan. 2010 to Jul. 2017. The incidence of thyroid cancer in those thyroid nodules with and without HT based on the postoperative pathological results was compared. Results Among 843 patients of thyroid benign nodules, 15.3% cases were complicated with HT. Of all the patients with malignant tumors, 365 cases were PTC, accounting for 96.5% of all malignant tumors, and among whom, 10.8% were complicated with HT. Of the 169 cases of thyroid nodules combined with HT, 23.7% patients had PTC. For patients with thyroid nodules without I-IT, 30.3% had FFC. The difference had no statistical significance （X^2=3.08,P〉0.05）. Conclusion Thyroid nodules complicated with HT doesn＇t increase the incidence of thyroid cancer.
作者
董华
张遵城
郭永涛
杨绍时
董萍
Dong Huo;Zhang Zuneheng;Guo Yongtao;Yang Shaoshi;Dong Ping(Department of Nuclear Medicine, the Second Hospital, Tianjin Medical University, Tianjin 300211, China;Department of Thyroid and Breast Surgery, the Second Hospital, Tianjin Medi- cal University, Tianjin 300211, China)
出处
《中华内分泌外科杂志》
CAS
2018年第3期244-246,共3页
Chinese Journal of Endocrine Surgery
