摘要
目的:分析采用不同起始剂量氨基酸对早产低出生体重儿早期营养状态的应用效果。方法:回顾性分析2018年6月~2020年6月间在某院治疗的82例早产低出生体重儿,患儿出生后24h内均给予对症治疗和小儿复方氨基酸营养治疗,根据氨基酸起始剂量的不同分为对比组(起始剂量为1.0g·kg-1·d-1)和研究组(起始剂量为2.0g·kg-1·d-1)各41例。对比两组患儿的治疗前、治疗半个月后的生化血气指标(血尿素氨、血氨、血肌酐、前白蛋白),并比较两组的头围增长速度、静脉营养天数、恢复出生体重日龄、住院天数、体质量增长速度。结果:治疗前两组血尿素氨、血氨、血肌酐、前白蛋白指标无统计学差异(P>0.05)。治疗后两组血尿素氨、血氨、血肌酐、前白蛋白指标均优于治疗前(P<0.05);研究组的血尿素氨、血氨、血肌酐、前白蛋白水平均高于对比组(P<0.05);研究组的头围增长速度、体质量增长速度快于对比组(P<0.05);研究组的静脉营养天数、恢复出生体重日龄、住院天数均短于对比组(P<0.05)。结论:在早产低出生体重儿出生后24h内进行高剂量氨基酸输注治疗,可明显提升患儿的血尿素氨、血氨、血肌酐、前白蛋白水平,加快体质量增长,促使患儿尽早恢复正常体重,应用效果较低起始剂量好。
Objective:To analyze the effect of different initial doses of amino acids on early nutritional status of preterm low birth weight infants.Methods:The data of 82 cases of premature low birth weight infants treated in a hospital from June 2018 to June 2020 were retrospectively analyzed.The children were given symptomatic treatment and compound amino acid nutrition therapy within 24 hours after birth.According to the different initial doses of amino acids,they were divided into the control group(the initial dose was 1.0g·kg-1·D-1)and the study group(the initial dose was 2.0g·kg-1·D-1),with 41 cases in each group.The biochemical blood gas indexes(blood urea ammonia,blood ammonia,serum creatinine,prealbumin)before treatment and half a month after treatment were compared between the two groups,and the growth rate of head circumference,days of intravenous nutrition,age of recovery of birth weight,length of hospital stay and growth rate of body mass were compared between the two groups.Results:Before treatment,there was no significant difference in blood urea ammonia,blood ammonia,serum creatinine and prealbumin between the two groups(P>0.05).After treatment,the blood urea ammonia,blood ammonia,serum creatinine,prealbumin indicators in the two groups were better than those before treatment(P<0.05);The blood urea ammonia,blood ammonia,serum creatinine,prealbumin levels in the study group were higher than those in the control group(P<0.05);The growth rate of head circumference and body weight in the study group was faster than that in the control group(P<0.05);The days of intravenous nutrition,the day of recovery of birth weight,and the length of hospital stay in the study group were shorter than those in the control group(P<0.05).Conclusion:High dose of amino acid infusion within 24 hours after birth of low birth weight premature infants can significantly improve the levels of blood urea ammonia,blood ammonia,serum creatinine and prealbumin,accelerate the growth of body weight,and promote the children to return to nor
作者
刘芳
Liu Fang(Department of Western Medicine,Nanyang No.1 People's Hospital,Nanyang 473000)
出处
《数理医药学杂志》
CAS
2021年第4期529-531,共3页
Journal of Mathematical Medicine
关键词
不同起始剂量
氨基酸
早产
低出生体重儿
早期营养状态
生化血气指标
different starting doses
amino acids
premature birth
low birth weight infants
early nutritional status
biochemical blood gas indicators
