摘要
目的比较5年前后的极早早产儿(出生胎龄28～31+周,VPI)住院期间一般情况、围生期因素、生长发育、营养支持及生长结局的差异。方法收集2010年1月1日～12月31日和2015年1月1日～12月31日江苏省淮安市妇幼保健院新生儿医学中心收治住院的VPI的资料。以出生后24 h内住院、达出院标准为入选标准,按出生年度分为2010年组(82例)和2015年组(134例),比较两组VPI的的一般情况和围生期情况。结果与2010年组比较,2015年组早产儿在出生胎龄、出生体质量、出院胎龄、出院体质量、极低出生体重儿发生率、住院天数、母亲胎盘早剥发生率的一般情况和围生期情况方面;最低体质量、恢复出生体质量时间、体质量增长速度、完全经口喂养时间、胃肠营养达418 kJ/(kg·d)时间、达全胃肠喂养时间、首次氨基酸使用日龄、氨基酸使用起始剂量、氨基酸累计使用时间、首次脂肪乳使用日龄、脂肪乳使用起始剂量、脂肪乳累计使用时间的生长发育及营养支持方面;总宫外生长迟缓(EUGR)发生率、轻度EUGR发生率的生长发育结局方面,差异均有统计学意义(P <0.05)。结论 VPI的生长发育及营养状况呈改善趋势。关注更低出生体质量、更小出生胎龄、合并更危重并发症的VPI,实施更积极的营养支持策略,可以获得更好的生长结局。
Objective To contrast the different general condition, perinatal factor, growing development, nutritional support and growth outcome status among very preterm infants （VPI） before and after 5 years. Methods The data of the VPI who treated in the Neonatal Medical Center of Huai＇an Maternity and Child Healthcare Hospital from January 1 to December 31, 2010 and January 1 to December 31, 2015. A total of 82 cases in 2010 and 134 cases in 2015 were divided into two groups according to the year of birth according to the inclusion criteria of hospitalization and discharge within 24 h after birth. Results The differences in the general condition and perinatal factor such as gestational age, birth weight, discharge gestational age, discharge body weight, incidence of very low birth weight infant, days of hospitalization, incidence of placental abruption in mothers; differences in the growing development and nutritional support such as minimum weight, restore birth weight time, growth rate, total enteral feeding time, time of gastrointestinal nutrition reach at 418 kJ/（kg·d）, total gastrointestinal feeding time, initial amino acid usage time, initial amino acid usage dosage, accumulated amino acid usage time, initial intralipid usage time, initial intralipid usage dosage, accumulated intralipid usage time; differences in the growth outcome： incidence of total Extrauterine growth retardation （EUGR）, incidence of mild EUGR were existed between the two groups the differences were statistically significant （P 〈 0.05）. Conclusion The growth and nutritional status of VPI are on a upward trend. Pay attention to the VPI with lower birth weight, lower gestational age and severe compli- cations, the more treatment and support in strategy paid, the better growth and hospital outcome gained.
作者
徐文英
丁素芳
张丽
王玉美
李敏
韩良荣
岳虹霓
XU Wenyin;DING Sufan;ZHANG Li;WANG Yumei;LI Min;HAN Liangrong;YUE Hongni(Child Care Divisionl Huai＇an Maternity and Child Healthcare Hospital Affiliated to Medical College of Yangzhou U-niversity,Jiangsu Province,Huai＇an 223002,China;Neonatal Medical Center,Huai＇an Maternity and Child Healthcare Hospital Affiliated to Medical College of Yangzhou University,Jiangsu Province,Huai＇an 223002,China)
出处
《中国医药导报》
CAS
2018年第29期70-73,共4页
China Medical Herald
基金
江苏省妇幼健康科研项目(F201507)
江苏省妇幼健康科研项目(F201402)
关键词
极早早产儿
生长发育
营养支持
生长结局
Very preterm infants
Growing development
Nutritional support
Growth outcome
