摘要
黄芪和人参为历代中医所推崇的扶正固本的良药,被广泛应用于保健食品和医药领域。黄芪多糖与人参多糖又分别为黄芪与人参的主要功效成分。现有大量的文献表明2种多糖具有增强免疫力、抗病毒等功效。由于多糖成分繁多,结构复杂,目前的研究多以聚合物的形式为主,不同分子量的多糖的单糖组成和比例不同,糖连接序列和糖苷键类型以及相应的生物学活性也不相同,且目前的研究尚未明确结构-活性关系。本文综述了黄芪多糖、人参多糖以及二者复配在免疫调节方面的药理作用及应用研究进展,为今后两者在保健食品免疫调节产品开发方面的应用提供参考。
Astragalus membranaceus and Panax ginseng are good medicines for strengthening the body and strengthening the foundation recommended by traditional Chinese medicine in the past dynasties,and are widely used in health food and medicine.Astragalus membranaceus polysaccharide and Panax ginseng polysaccharide are the main functional components of astragalus and ginseng respectively.A large number of literatures have shown that two polysaccharides have the effects of enhancing immunity and anti-virus.Due to the various components and complex structures of polysaccharides,the current research is mostly in the form of polymers.The composition and proportion of monosaccharides of polysaccharides of different molecular weights are different,and the sugar linkage sequence,glycosidic bond types and corresponding biological activities are also different.Current research has not clarified the structure-activity relationship.This article reviewed the pharmacological effects and application research progress of Astragalus membranaceus polysaccharide,Panax ginseng polysaccharide and their combination in immunomodulation,so as to provide reference for the future application of the two in the development of health food immunomodulation products.
作者
王玥
杨志国
王艳华
李建
王丹
李丽维
WANG Yue;YANG Zhi-Guo;WANG Yan-Hua;LI Jian;WANG Dan;LI Li-Wei(Tasly Academy,Tianjin 300410,China;Tianjin Tasly(Liaoning)Pharmaceutical Co.,Ltd.,Fuxin 123000,China)
出处
《食品安全质量检测学报》
CAS
北大核心
2021年第3期891-897,共7页
Journal of Food Safety and Quality
关键词
黄芪多糖
人参多糖
成分组成
免疫调节
Astragalus membranaceus polysaccharides
Panax ginseng polysaccharides
composition
immunoregulation
