摘要
目的探究超微经皮肾镜碎石术(UMP)与体外冲击波碎石术(ESWL)治疗肾结石合并糖尿病患者的效果及对d清中性粒细胞明胶酶相关载脂蛋白(NGAL)和血红蛋白(Hb)水平的影响。方法选取2017年1月至2019年1月经本院收治的108例肾结石合并糖尿病患者作为研究对象,采用简单随机化原则将其分为两组.每组各54例。对照组患者采用ESWL.进行治疗,观察组患者采用UMP进行治疗。比较观察两组患者的结石清除率、术中出血量.术后住院时间、NGAL及Hb水平,并比较术后并发症。结果两组患者的结石清除率比较,差异无统计学意义(P>0.05);观察组的手术时间、术中出血量、术后住院的时间明显低于对照组(P<0.01)。术前两组患者的血清NGAL水平比较,差异无统计学意义(P>0.05);术后12h,两组患,者的血清NGAL水平达到峰值,观察组患者的血清NGAL水平在术后24.48及72 h均明显低于对照组(P<0.01);术后观察组的血红蛋白水平低于对照组(P<0.05);术后观察组肾绞痛、肾包膜下血肿严重血尿、发热等并发症发生率明显低于对照组(P<0.05)。结论UMP治疗肾结石合并糖尿病患者的效果疗效佳,值得推广。
Objeetive To investigate the efet of ultra-mini percutaneous(UMP)and extra-corporeal shock wave lithotripsy(ESWL)on the treatment of renal calculi with diabetes mellitus and its ffeet on serum neutro-philgelatase-associated lipocalin(NGAL)and Hemoglobin(Hb)levels.Meth-ods From January 2017 to January 2019,108 patients with kidney stones and diabetes mellitus were selected as the research objects.The patients were divided into two groups by simple randomization.The control group was treated by ESWL,while the observation group was treated by UMP.The caleuli removal,intraoperative blood loss,postoperative hospital stay and NGAL level of the two groups were compared and observed.Postoperative Hb was detected in patients and postoperative complications were compared.Results The resuls of this study showed that there was no difference in the caleulus clearance rale between the two groups after treatment(P>0.05).The operation time,blood loss and postoperative hospitalization time were significantly lower in the observation group(P<0.01).There was no difference in serum NGAL between the two groups before surgery(P>0.05).At 12 h after surgery,the serum NGAL level in the two groups reached a peak(P<0.01).The serum NGAL levels of patients in the observation group were signifcantly lower than those in the control group at 24,48 and 72 hours after surgery(P<0.01).The serum NGAL level of the observation group was signifi-canly lower at 72 hours after surgery(P>0.05).The incidence of complications such as renal colic,subcapsular hematoma,severe hematuria and fever in the observation group was significantly lower than that in the control group(P<0.05).Conclusions The ffet of UMP in the treatment of renal calculi combined with diabetes is good.
作者
何霁
袁宁
孙娜
黄秋鹏
He Ji;Yuan Ning;Sun Na;Huang Qiupeng(Department of Endocrinology,Nanchong Central Hospital,Nanchong,637000)
出处
《国际泌尿系统杂志》
2021年第2期294-297,共4页
International Journal of Urology and Nephrology
