摘要
目的:探讨不同浓度臭氧联合射频消融术(RFA)治疗神经根型颈椎病(CSR)的临床疗效,为临床选择最适宜的臭氧浓度提供参考依据。方法:选择某院收治的90例CSR患者,采用随机数字表法分为3组:研究组A、研究组B和对照组,各30例。对照组予以RFA治疗,研究组A予以RFA联合40 mg/L浓度的臭氧注射治疗,研究组B予以RFA联合60 mg/L浓度的臭氧注射治疗。比较3组患者治疗后视觉模拟评分(VAS)、颈椎功能评分、炎性因子水平及临床疗效。结果:治疗后3组患者VAS评分及IL-6、IL-8和hs-CRP水平均明显下降,且表现为研究组B<研究组A<对照组,差异有统计学意义(P<0.05);治疗后,所有患者颈椎功能评分均明显提高,且研究组B>研究组A>对照组,差异有统计学意义(P<0.05);3组患者均取得满意疗效,对照组优良率为50.0%,研究组A和研究组B分别为56.7%和73.3%,表现为研究组B>研究组A>对照组,差异有统计学意义(P<0.05)。结论:RFA联合臭氧治疗CSR的综合疗效优于单纯RFA,且注射60 mg/L浓度的臭氧优于40 mg/L浓度。
Objective:To investigate the clinical efficacy of different concentrations of ozone combined with radiofrequency ablation(RFA)in the treatment of cervical spondylotic radiculopathy(CSR)and to provide a reference for clinical selection of the most appropriate ozone concentration.Methods:90 patients with CSR were randomly divided into three groups:study Group A,study group B and a control group,with 30 cases in each group.The 30 cases in the control group were treated with RFA only,study Group A was treated with RFA combined with ozone injection of 40 mg/L,and study Group B was treated with RFA combined with ozone injection of 60 mg/L.Visual analogue scale(VAS),cervical spine functional score,levels of inflammatory factors,and clinical effect after the treatment were compared among the three groups.Results:All patients in the 3 groups successfully completed RFA or RFA combined with ozone injection.After the treatment,VAS scores,and serum inflammatory factors(il-6,il-8 and hs-crp)were significantly lower than those before the treatment,with the result of study Group B<study Group A<control group(P<0.05).After the treatment,the cervical spine functional scores of all patients were significantly improved,with the result of study Group B>study group A>control group(P<0.05).All the patients in the three groups achieved satisfactory curative effects,and the excellent and good rates were 50.0%,56.7%and 73.3%respectively in the control group,study Group A and study Group B,with statistically significant differences(P<0.05).Conclusion:The comprehensive efficacy of RFA combined with ozone in the treatment of CSR is better than that of RFA alone,and the ozone injection concentration of 60 mg/L is better than that of 40 mg/L.
作者
齐文斌
QI Wenbin(Department of Pain Treatment, The Traditional Chinese Medicine Hospital of Jiaozuo, Henan 450000, China)
出处
《淮海医药》
CAS
2021年第1期17-20,共4页
Journal of Huaihai Medicine
关键词
神经根型颈椎病
浓度
臭氧
射频消融术
Cervical spondylotic radiculopathy
Concentration
Ozone
Radiofrequency ablation