摘要
目的观察雷火灸配合羌活胜湿汤治疗风寒痹阻型神经根型颈椎病的临床疗效及其对血清白细胞介素-6(interleukin-6,IL-6)、肿瘤坏死因子-α(tumor necrosis factor-α,TNF-α)水平的影响。方法将80例风寒痹阻型神经根型颈椎病患者随机分为治疗组和对照组,每组40例。对照组采用羌活胜湿汤治疗,治疗组在对照组基础上采用雷火灸治疗。记录两组患者治疗前后血清IL-6、TNF-α水平的差异及简化McGill疼痛问卷(short-form McGill pain questionnaire,SF-MPQ)各项评分[疼痛评估指数(pain rating index,PRI)、视觉模拟评分法(visual analog scale,VAS)、现时疼痛强度(present pain intensity,PPI)评分]、颈椎功能障碍指数(neck disability index,NDI)评分的变化情况,并比较两组临床疗效。结果两组治疗后MPQ各项评分、NDI评分及血清IL-6、TNF-α水平均较同组治疗前显著降低,差异均具有统计学意义(P<0.05)。治疗组治疗后MPQ各项评分、NDI评分及血清IL-6、TNF-α水平均明显低于对照组,差异均具有统计学意义(P<0.05)。治疗组总有效率为94.3%,明显高于对照组的75.0%,两组比较差异具有统计学意义(P<0.05)。结论雷火灸配合羌活胜湿汤治疗风寒痹阻型神经根型颈椎病疗效确切。
Objective To observe the clinical efficacy of thunder-fire moxibustion plus Qianghuo dampness-eliminating decoction for cervical spondylotic radiculopathy of wind-cold obstruction type and its effect on serum interleukin-6(IL-6)and tumor necrosis factor-α(TNF-α)levels.Method Eighty patients with cervical spondylotic radiculopathy of wind-cold obstruction type were randomized to treatment and control groups,with 40 cases in each group.The control group was treated with Qianghuo dampness-eliminating decoction and the treatment group,by thunder-fire moxibustion in addition.Serum IL-6 and TNF-αlevels were measured and the short-form Mcgill pain questionnaire(SF-MPQ)[including the pain rating index(PRI),the visual analog scale(VAS)and the present pain intensity(PPI)]item scores and the neck disability index(NDI)score were recorded in the two groups before and after treatment.The clinical therapeutic effects were evaluated.Result The MPQ item scores and the NDI score,and serum IL-6 and TNF-αlevels decreased significantly in the two groups after treatment compared with before with statistical significant differences(P<0.05).After treatment,the MPQ item scores and the NDI score,and serum IL-6 and TNF-αlevels were significantly lower in the treatment group than in the control group with before with statistical significant differences(P<0.05).The total efficacy rate was 94.3%in the treatment group,which was significantly higher than 75.0%in the control group with a statistical significant difference between the two groups(P<0.05).Conclusion Thunder-fire moxibustion plus Qianghuo dampness-eliminating decoction has a definite therapeutic effect on cervical spondylotic radiculopathy of wind-cold obstruction type.
作者
陈增
王建强
陈晓庆
李亚平
甘伟
王发潮
CHEN Zeng;WANG Jianqiang;CHEN Xiaoqing;LI Yaping;GAN Wei;WANG Fachao(Geriatric Hospital of Hainan,Haikou 570100,China)
出处
《上海针灸杂志》
CSCD
2023年第11期1190-1194,共5页
Shanghai Journal of Acupuncture and Moxibustion
基金
海南省基础与应用基础研究计划(自然科学领域)高层次人才项目(2019RC393)
海南省临床医学中心建设项目
海南省卫生健康行业科研项目(20A200494,21A200425,21A200433)。
关键词
灸法
雷火灸疗法
颈椎病
神经根病
风寒痹阻
羌活胜湿汤
白细胞介素-6
肿瘤坏死因子-α
Moxibustion
Thunder-fire moxibustion therapy
Spondylosis
Radiculopathy
Wind-cold obstruction
Qianghuo dampness-eliminating decoction
Interleukin-6
Tumor necrosis factor-α
