摘要
目的以Meta分析的方法研究DCE-MRI定量参数Ktrans和Ve对胶质瘤级别的评估能力。方法在CNKI、万方、维普以及Pubmed数据库中检索近10年与DCE-MRI对胶质瘤级别的鉴别能力有关的中英文文献,通过Endnote-X9软件导入后,根据预先设定的纳入标准及排除标准进行筛选,并进行文献质量的评估,然后使用RevMan5.3软件进行Meta分析。结果共检索到501篇相关文献,最终纳入15篇文献,共计587名患者。经过对数据的Meta分析后发现高级别胶质瘤的DCE-MRI定量参数Ktrans、Ve均显著高于低级别胶质瘤。结论 DCE-MRI定量参数Ktrans、Ve能够对胶质瘤分级诊断提供帮助,从而协助临床对术前治疗方式的选择以及对预后情况的判断。
Objective To investigate the ability of DCE-MRI quantitative parameters Ktrans and Ve to assess glioma grade by meta-analysis.Methods Chinese and English literatures related to the ability of DCE-MRI to differentiate glioma grades were searched in the CNKI, Wanfang, Weipu, and Pubmed databases for nearly 10 years, after import through Endnote-X9 software, according to pre-set inclusion criteria. Screening was performed with exclusion criteria and literature quality was assessed, followed by Meta analysis using RevMan5.3 software.Results A total of 501 related articles were retrieved, and 15 articles were eventually included, for a total of 587 patients. After meta-analysis of the data, the DCE-MRI quantitative parameters Ktrans and Ve of high-grade gliomas were significantly higher than those of low-grade gliomas.Conclusion The DCE-MRI quantitative parameters Ktrans and Ve can help the grading diagnosis of glioma, which can assist the clinical choice of preoperative treatment and judgment of prognosis.
作者
张剑男
罗琳
陈强
渠倬然
ZHANG Jian-nan;LUO Lin;CHEN Qiang;QU Zhuo-ran(Graduate School of Baotou Medical College,Inner Mongolia University of Science and Technology,Baotou 014040 China;The First Affiliated Hospital of Baotou Medical College,Inner Mongolia University of Science and Technology,Baotou 014010 China)
出处
《内蒙古医学杂志》
2021年第1期19-23,共5页
Inner Mongolia Medical Journal
