摘要
目的:观察益母败酱汤联合西药治疗慢性盆腔炎的临床疗效。方法:将112例患者随机分为观察组和对照组,每组56例。对照组予以康妇消炎栓治疗,观察组予以益母败酱汤治疗。观察治疗后两组临床疗效、临床症状缓解时间、血流动力学指标、血液流变学指标及淀粉样蛋白A(amyloid A,SAA),白细胞介素6(interleukin-6,IL-6)和触珠蛋白(haptoglobin,HPT)水平。结果:总有效率观察组为94.64%(53/56),对照组为78.57%(44/56),两组比较差异有统计学意义(P<0.05)。观察组盆腔肿块消失、白带恢复、下腹腰骶痛缓解、腹痛缓解和精疲乏力缓解时间明显短于对照组(P<0.01)。治疗后两组血流阻力指数(resistance index,RI),搏动指数(pulsative index,PI),全血高、中、低切黏度,血浆黏度,SAA、IL-6和HPT较治疗前明显降低(P<0.01),而最大血流速度(maximum velocity,Vmax)和收缩期峰值血流速度(peak systolic velocity,PSV)水平较治疗前明显升高(P<0.01),上述指标观察组的改善水平均优于对照组(P<0.01)。结论:益母败酱汤联合西药治疗慢性盆腔炎可缓解临床症状,降低血液黏度,改善血流动力学指标,提高临床有效率,可能与益母败酱汤降低机体SAA、IL-6和HPT水平有关。
Objective:To observe clinical effects of Yimu Baijiang decoction combined with Western medicine in the treatment for chronic pelvic inflammatory disease.Methods:All 112 patients were randomized into the observation group and the control group,56 cases each group.The control group were given Kangfu Xiaoyan suppository,and the observation group Yimu Baijiang decoction.To observe clinical effects,clinical symptom relief time,hemodynamic parameters,hemorheological indexes and the levels of SAA,IL-6 and HPT after treating in both groups.Results:Total effective rate of the observation group was 94.64%(53/56),higher than 78.57%(44/56)of the control group,and the difference was statistically significant(P<0.05).The observation group was shorter than the control group in pelvic mass disappearing time,leukorrhoea recovery time,relief time of lumbosacral pain in lower abdomen,abdominal relief time,relief time of fatigue and weakness notably(P<0.01).After treating,RI,PI,high,medium and low shear viscosity of whole blood,plasma viscosity,SAA,IL-6 and HPT of both groups after treating lowered compared with these before treating(P<0.01),while Vmax and PSV rose than before treating notably(P<0.01),the improvements of the observation group were superior to these of the control group in these indexes above(P<0.01).Conclusion:Yimu Baijiang decoction combined with Western medicine in the treatment for chronic pelvic inflammatory disease could relieve clinical symptoms,reduce blood viscosity,improve hemodynamic parameters,lift clinical effective rate,and it might be related to that Yimu Baijiang decoction could reduce the levels of SAA,IL-6 and HPT.
作者
汪琼
张锋
杨振
WANG Qiong;ZHANG Feng;YANG Zhen(Minhang District Hospital of Integrated Traditional Chinese and Western Medicine,Shanghai 200240,China;Shanghai City Fire Brigade Hospital;Shanghai Garrison Jing′an First Departed Cadre Sanatorium)
出处
《西部中医药》
2021年第2期96-99,共4页
Western Journal of Traditional Chinese Medicine
