摘要
目的探讨CT Bhalla评分对支气管扩张患者预后的评估价值。方法纳入南京鼓楼医院集团宿迁市人民医院2016年1月—2018年12月收治的支气管扩张患者80例,患者入院后,均行CT Bhalla评分。收集患者的临床资料,包括性别、年龄、体重指数、危险分级、吸烟史、病程年限、急性加重次数、铜绿假单胞菌阳性、第1秒用力呼气容积占预计值的百分比(FEV1%pred),分析CT Bhalla评分与患者临床特征的关系。随访12个月,分析患者预后情况,并根据预后情况将其分为良好组(16例)和不良组(64例)。比较两组CT Bhalla评分,绘制受试者工作特征曲线(ROC)分析CT Bhalla评分对支气管扩张患者预后的预测价值。结果患者CT Bhalla评分(5~17)分,平均(9.27±1.26)分;不同年龄、危险分级、病程年限、急性加重次数、铜绿假单胞菌阳性、FEV1%pred患者CT Bhalla评分比较,差异均有统计学意义(均P<0.05)。其中高危患者的CT Bhalla评分显著高于中危患者与低危患者,中危患者高于低危患者,且急性加重≥3次/年显著高于急性加重2次/年的患者与急性加重1次/年的患者,急性加重2次/年的患者高于急性加重1次/年的患者,差异均有统计学意义(均P<0.05)。不良组CT Bhalla评分显著高于良好组,差异有高度统计学意义(P<0.01)。CT Bhalla评分评价患者预后不良的AUC为0.731(标准误=0.065,95%CI=0.603~0.859,P=0.002),最佳界值为9.490分,敏感度为72.70%,特异性为65.90%。结论CT Bhalla评分对支气管扩张患者预后有一定预测价值。
Objective To explore the estimated value of the prognosis of patients with bronchiectasis by CT Bhalla score.Methods A total of 80 patients with bronchiectasis admitted to Suqian People’s Hospital of Nanjing Drum-Tower Hospital Group from January 2016 to December 2018 were included.After admission,all patients received CT Bhalla score.Clinical data of the patients were collected,including gender,age,body mass index,risk grade,smoking history,duration of disease,number of acute exacerbations,Pseudomonas aeruginosa positiveness,percentage of forced expiratory volume in the first second to the predicted value(FEV1%pred),and the relationship between CT Bhalla score and clinical characteristics of the patients was analyzed.The patients were followed up for 12 months to analyze the prognosis,and were divided into good group(16 cases)and bad group(64 cases)according to the conditions of prognosis.CT Bhalla score was compared between the two groups,and receiver operating characteristic curve(ROC)was drawn to analyze the predictive value of CT Bhalla score in the prognosis of patients with bronchiectasis.Results CT Bhalla scores ranged from five to seventeen,with an average score of(9.27±1.26).There were statistically significant differences in CT Bhalla scores among patients with different ages,risk grade,duration of disease,number of acute exacerbations,Pseudomonas aeruginosa positiveness and FEV1%pred(all P<0.05).Among them,the CT Bhalla scores of high risk patients were significantly higher than those of medium risk patients and low risk patients,and medium risk patients were higher than those of low risk patients,and patients with acute exacerbations≥three times per year were significantly higher than those with acute exacerbations two times per year and those with acute exacerbations one time per year.Patients with acute exacerbations two time sper year were significantly higher than those with acute exacerbations one time per year,with statistically significant differences(all P<0.05).CT Bhalla score in the ba
作者
周洁
翁婷
高蔚
ZHOU Jie;WEN Ting;GAO Wei(Department of Radiology,Suqian Hospital Affiliated to Xuzhou Medical UniversitySuqian People’s Hospital of Nanjing Drum-Tower Hospital Group,Jiangsu Province,Suqian223800,China;Department Pneumology,Suqian Hospital Affiliated to Xuzhou Medical UniversitySuqian People’s Hospital of Nanjing Drum-Tower Hospital Group,Jiangsu Province,Suqian223800,China)
出处
《中国医药导报》
CAS
2021年第5期121-124,138,共5页
China Medical Herald
基金
江苏省卫生计生委指导性科研课题(Z201605)。
