摘要
益生菌是一类对人体和动物体有益的菌,作为肠道内的正常微生物优势菌群,可调节菌群失调,促使肠道微生态恢复平衡。对肠道菌群与人类健康关系的深入研究发现,益生菌可对机体进行免疫调节、补充并调节肠道菌群,维持肠道微环境平衡,保护肠黏膜屏障功能、影响多种细胞因子以提高肠道免疫性能,可用于儿童手足口病的辅助治疗,明显缩短皮疹好转及消退时间、体温、食欲恢复正常的时间,是辅助治疗手足口病的有效方法。本文就目前益生菌辅助治疗手足口病的作用机制及临床应用进行阐述。
Probiotics are a kind of bacterium that have been proved by scientists to be beneficial to human beings and animals.As the dominant flora of normal microorganisms in the intestinal tract,probiotics can regulate the imbalance of flora and promote the restoration of intestinal microecology.Further research on the relationship between the intestinal flora and human health found that probiotics could regulate the body’s immunity,supplement and regulate the intestinal flora,maintain the balance of intestinal microenvironment,protect the barrier function of intestinal mucosa,and affect a variety of cytokines to improve the intestinal immune performance,thus could be applied in the adjuvant treatment of hand-feet-mouth disease.Probiotics significantly shortened the time of improvement and regression of rash and the time for body temperature and appetite to return to normal.The mechanism and clinical application of probiotics in the treatment of hand-feet-mouth disease are introduced in this paper.
作者
庞颖颖
张玉玲
PANG Ying-ying;ZHANG Yu-ling(The Second Affiliated Hospital of Harbin Medical University,Harbin 150081,China)
出处
《食品与药品》
CAS
2021年第1期I0001-I0005,共5页
Food and Drug
关键词
益生菌
手足口病
肠道菌群
黏膜屏障
免疫调节
细胞因子
probiotic
hand-feet-mouth disease
intestinal flora
mucosal barrier
immune regulation
cytokine
