摘要
目的探讨内镜配合喷洒血凝酶、质子泵抑制剂(PPI)治疗消化性溃疡出血的临床疗效。方法选取2018年1月—2019年12月收治的消化性溃疡伴出血患者383例,根据入院顺序随机分为对照组(191例)与观察组(192例),对照组患者接受静脉滴注PPI治疗(兰索拉唑),观察组患者在此基础上联合内镜下喷洒血凝酶治疗。收集2组患者的止血效果(止血时间、输血量、住院时间)、预后情况(48 h内出血情况、转开腹手术情况)以及总体止血效果等进行对比分析。结果观察组患者止血时间和住院时间均短于对照组(P<0.05),输血量亦少于对照组(P<0.05)。观察组患者中48 h内停止出血者比例高于对照组,转开腹手术治疗和再出血患者比例低于对照组(P<0.05),且总体止血效果优于对照组(P<0.05)。结论对于消化性溃疡伴出血患者,联合使用静脉泵入PPI和内镜下喷洒血凝酶治疗,能够显著提升止血有效率,改善预后,值得推广。
Objective To explore the clinical effect of endoscopic therapy combined with spraying hemagglutinin and PPI in the treatment of peptic ulcer bleeding.Methods 383 patients with peptic ulcer and bleeding admitted from January 2018 to December 2019 were randomly divided into control group(191 cases)and observation group(192 cases)according to the order of admission.The patients in the control group were treated with PPI(LANsola azole),and the patients in the observation group were treated with hemocoagulase under endoscope.The data of hemostasis effect(hemostasis time,blood transfusion volume,hospitalization time),prognosis(bleeding within 48 hours,conversion to open surgery)and overall hemostasis effect were collected and analyzed.Results The hemostasis time and hospitalization time of patients in the observation group were shorter than those in the control group(P<0.05),and the amount of blood transfusion was also less than that in the control group(P<0.05).The proportion of patients who stopped bleeding within 48 hours in the observation group was higher than that in the control group,and the proportion of patients who switched to open surgery and rebleeding was lower than that in the control group(P<0.05),and the overall hemostasis effect was better than that in the control group(P<0.05).Conclusions For patients with peptic ulcer and bleeding,the combination of intravenous pump PPI and endoscopic spraying of hemagglutinin can significantly improve the efficiency of hemostasis and help patients improve prognosis.
作者
梁丽燕
陈健
苏有盛
Liang Liyan;Chen Jian;Su Yousheng(The First People's Hospital of Zhaoqing City,Zhaoqing,Guangdong 526400)
出处
《基层医学论坛》
2021年第4期472-474,共3页
The Medical Forum
