摘要
文章主要对近5年来多酚化合物抑制黄嘌呤氧化酶活性、抑制类型及相互作用研究进行了综述,并对其构效关系、结构修饰及金属配合物的开发与应用进行了展望,以期为多酚化合物作为降尿酸食品功能因子和药物的研发提供参考。
The inhibitory activities and types of polyphenolic compounds on xanthine oxidase and their interactions in the past five years was summarized in this review,and the structure-activity relationship,the structural modification and its development and application of metal complex were also prospected.This will provide some references for the research and development of polyphenolic compounds as lowing uric acid food functional factors and drugs.
作者
洪鑫月
吴健妹
罗小乔
刘凯
周伟杰
张国文
HONG Xin-yue;WU Jian-mei;LUO Xiao-qiao;LIU Kai;ZHOU Wei-jie;ZHANG Guo-wen(State Key Laboratory of Food Science and Technology,Nanchang University,Nanchang,Jiangxi 330047,China)
出处
《食品与机械》
北大核心
2021年第2期1-8,共8页
Food and Machinery
基金
国家自然科学基金项目(编号:22078143)
江西省自然科学基金项目(编号:20202BAB205005)
食品科学与技术国家重点实验室项目(编号:SKLF-ZZB-201914,SKLF-ZZA-201912)。
关键词
多酚化合物
黄嘌呤氧化酶
抑制活性
相互作用
polyphenolic compounds
xanthine oxidase
inhibitory activity
interaction