摘要
目的探讨血液净化对重度脓毒血症患者血清炎性细胞因子、预后的影响。方法选取2018年7月至2019年11月我院收治的重度脓毒血症患者50例,随机分为基础组(基础治疗,25例)和干预组(基础治疗联合血液净化治疗,25例)。比较两组患者治疗前后的血清炎性细胞因子水平以及预后。结果治疗3 d后,两组的CRP、PCT、TNF-α、IL-6水平均显著低于治疗前,且干预组的CRP、PCT、TNF-α、IL-6水平均显著低于基础组(P<0.05)。干预组的预后显著优于基础组(P<0.05)。结论血液净化可有效降低重度脓毒血症患者的血清炎性细胞因子水平,改善预后。
Objective To explore the impact of blood purification on serum inflammatory cytokines and prognosis of patients with severe sepsis.Methods 50 patients with severe sepsis admitted to our hospital from July 2018 to November 2019 were selected and randomly divided into the basic group(basic treatment,25 cases)and the intervention group(basic treatment combined with blood purification treatment,25 cases).The levels of serum inflammatory cytokines before and after treatment and the prognosis were compared between two groups.Results After 3 days of treatment,the levels of CRP,PCT,TNF-αand IL-6 in both groups were significantly lower than those before treatment,and the levels of CRP,PCT,TNF-αand IL-6 of intervention group were significantly lower than those of basic group(P<0.05).The prognosis of intervention group was significantly better than that of basic group(P<0.05).Conclusions Blood purification can effectively reduce the level of serum inflammatory cytokines and improve the prognosis of patients with severe sepsis.
作者
林耀国
LIN Yaoguo(Department of Critical Care Medicine,Dongguan Dalang Hospital,Dongguan 523770,China)
出处
《临床医学工程》
2021年第2期197-198,共2页
Clinical Medicine & Engineering
