摘要
目的调查新型冠状病毒肺炎疫情对重症监护病房多药耐药鲍氏不动杆菌(Multidrug-Resistant Acinetobacter,MDR-AB)的影响,为指导医院感染防控措施提供参考。方法收集2019年1月-2020年8月新疆石河子大学第一附属医院综合ICU1、综合ICU2、神经外科ICU MDR-AB监测资料,现场观察ICU医护人员与物体表面的接触次数,使用荧光标记和环境微生物培养调查新型冠状病毒肺炎疫情前后ICU物体表面的荧光标记清除率,自然菌菌落数及MDR-AB检出数,应用Pearson相关分析环境中MDR-AB检出率与MDR-AB感染率之间的关系。结果ICU高频接触表面依次为床栏(43.59次)、被子(39.58次)、治疗车(30.83次)、静脉管路(27.46次)、护理站桌面(27.20次)、手消按钮(26.40次);新型冠状病毒肺炎疫情后荧光标记清除率和环境微生物采样合格率分别为81.35%和56.57%高于新型冠状病毒肺炎疫情前(P<0.001);新型冠状病毒肺炎疫情后环境中MDR-AB检出率和感染率分别为5.40%和1.80%低于新型冠状病毒肺炎疫情前(P<0.001),Pearson相关分析显示ICU环境中MDR-AB检出率和患者MDR-AB感染率存在正相关关系(r=0.850,P=0.002)。结论新型冠状病毒肺炎疫情防控促进了环境清洁消毒与隔离措施的落实,切断了多药耐药鲍氏不动杆菌的传播途径,对感染防控起到了积极的作用。
OBJECTIVE To investigate the effect of novel coronavirus pneumonia pandemic on multidrug-resistant Acinetobacter baumannii transmission in intensive care units(ICU)and to provide reference for the guidance of nosocomial infection prevention and control.METHODS Data of multidrug-resistant A.baumannii in ICU1,ICU2 and neurosurgery ICU from Jan.2019 to Aug.2020 were collected.Contact times between healthcare workers and environmental surfaces,clearance rate of fluorescent marker in the culture of environment specimens before and after the novel coronavirus pneumonia outbreak,number of free colonies and number of MDR-AB were detected,and the correlation between MDR-AB detection rate of the environment and MDR-AB the infection rate were analyzed by using Pearson correlation analysis.RESULTS The high-frequency contact surfaces in ICU were bed bars(43.59 times),quilts(39.58 times),treatment vehicles(30.83 times),vein tubes(27.46 times),nursing station table tops(27.20 times)and hand sterilized buttons(26.40 times).The clearance rate of fluorescent marker after novel coronavirus pneumonia outbreak was 81.35%,which was significantly higher than that before the new coronavirus-infected pneumonia epidemic outbreak(P<0.001),with the rate of 56.57%.The detection rate and infection rate of MDR-AB in the environment after new coronavirus-infected pneumonia epidemic were 5.40%and 1.80%,respectively,which were significantly lower than that before the epidemic(P<0.001).Pearson correlation analysis showed that the detection rate of MDR-AB in the ICU environment was positively correlated with the MDR-AB infection rate of patients(r=0.850,P=0.002).CONCLUSION Methods of novel coronavirus pneumonia epidemic prevention promoted the implementation of environmental sanitation,disinfection and isolation measures,cut off the transmission route of multidrug-resistant A.baumannii,and played a positive role in the prevention and control of infection.
作者
黄芳
李静
孙洁
张焱
段伟
张红梅
胡莲
何文英
HUANG Fang;LI Jing;SUN Jie;ZHANG Yan;DUAN Wei;ZHANG Hong-mei;HU Lian;HE Wen-ying(Shihezi University School of Medicine,Shihezi,Xinjiang 832008,China;不详)
出处
《中华医院感染学杂志》
CAS
CSCD
北大核心
2020年第24期3686-3691,共6页
Chinese Journal of Nosocomiology
基金
新疆维吾尔自治区重大科技专项基金资助项目(202013228)。
关键词
新型冠状病毒肺炎疫情
重症监护病房
多药耐药鲍氏不动杆菌
传播途径
Novel coronavirus pneumonia
Intensive care unit
Multidrug-resistant Acinetobacter baumannii
Route of transmission
