摘要
目的:探究进展性脑梗死(PCI)的危险因素,为临床预防及改善预后提供依据。方法:随机选取2017年6月-2019年6月本院收治的200例急性脑梗死患者作为研究对象。收集临床基线数据、实验室检查资料、影像学资料等,根据患者入院时及病情最重时行美国国立卫生院脑卒中量表(NIHSS)评分差值将其分为进展性脑梗死组(PCI组)(n=68)和非进展性脑梗死组(非PCI组)(n=132)。比较两组的临床资料(一般资料、生化指标、颈部血管彩超、影像学资料)。采用Logistic回归分析PCI的危险因素。结果:两组不同年龄、性别、吸烟史、冠心病史、饮酒史、血尿酸、血同型半胱氨酸(Hcy)、低密度脂蛋白胆固醇(LDL-C)比较,差异无统计学意义(P>0.05);不同白细胞计数、平均动脉压、血糖(Glu)、糖尿病史、发热、颈内动脉狭窄、颅内动脉狭窄、CT早期脑梗死征象[局灶低密度改变和大脑中动脉高密度征(HMCAS)]、脑分水岭梗死(CWI)、重度脑微出血(病灶>10个)方面比较,差异有统计学意义(P<0.05)。Logistic回归分析显示,糖尿病史、发热、白细胞计数、平均动脉压、Glu、颈内动脉狭窄、颅内动脉狭窄、CT早期脑梗死征象、CWI、重度脑微出血(病灶>10个)为PCI的独立危险因素(P<0.05)。结论:糖尿病史、发热、白细胞计数、Glu、颈内动脉狭窄、颅内动脉狭窄、CT早期脑梗死征象、CWI、重度脑微出血(病灶>10个)为PCI的独立危险因素,临床上治疗与预防应予以重视。
Objective:To explore the risk factors of progressive cerebral infarction (PCI) in order to provide evidence for clinical prevention and prognosis improvement.Method:A total of 200 patients with acute cerebral infarction (ACI) who were admitted to the hospital from June 2017 to June 2019 were randomly selected as the research objects.The clinical baseline data,laboratory examination data and imaging data were collected.According to difference values of National Institutes of Health Stroke Scale (NISS) scores at admission and at their severest status,they were divided into the PCI group (n=68) and the non-PCI group (n=132).The clinical data (general data,biochemical indexes,cervical vascular color Doppler ultrasound,imaging data) were compared between the two groups.The risk factors of PCI were analyzed by Logistic regression analysis.Result:There were no significant differences in age,gender,smoking history,coronary heart disease history,drinking history,blood uric acid,serum homocysteine (Hcy) and low-density lipoprotein cholesterol (LDL-C) between the two groups (P>0.05).There were significant differences in white blood cell count,mean arterial pressure,blood glucose (Glu),diabetes history,fever,internal carotid stenosis,intracranial artery stenosis,early cerebral infarction signs by CT[focal low-density changes,hyper-dense middle cerebral artery sign (HMCAS)]and cerebral watershed infarction (CWI),severe cerebral micro hemorrhage (lesions more than 10) (P<0.05).Logistic regression analysis showed that diabetes history,fever,white blood cell count,mean arterial pressure,Glu,internal carotid stenosis,intracranial artery stenosis,early cerebral infarction signs by CT,CWI,severe cerebral micro hemorrhage (lesions more than 10) were independent risk factors of PCI (P<0.05).Conclusion:Diabetes history,fever,white blood cell count,Glu,internal carotid stenosis,intracranial artery stenosis,early cerebral infarction signs by CT,CWI and severe cerebral micro hemorrhage (lesions more than 10) are independent risk factors
作者
陈晓娟
CHEN Xiaojuan(Nanping People’s Hospital Affiliated to Fujian University of Traditional Chinese Medicine,Nanping 353000,China)
出处
《中外医学研究》
2021年第2期17-20,共4页
CHINESE AND FOREIGN MEDICAL RESEARCH
关键词
进展性脑梗死
危险因素
糖尿病史
血糖
发热
CT早期脑梗死征象
脑分水岭梗死
脑微出血
Progressive cerebral infarction
Risk factor
Diabetes history
Glu
Fever
Early cerebral infarction sign by CT
Cerebral watershed infarction
Cerebral micro hemorrhage
