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黄连温胆汤加减治疗心悸(室性早搏)痰火扰心证的中医证候改善及预后分析 被引量:16

TCM Syndrome Improvement and Prognosis Analysis of Using Huanglian Wendan Decoction in the Treatment ofPalpitation(Ventricular Premature Beat)with Phlegm Fire Disturbing Heart Syndrome
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摘要 目的:探讨黄连温胆汤加减治疗心悸(室性早搏)痰火扰心证的中医证候改善及预后情况,为临床治疗提供依据。方法:选取我院2018年1月~2020年1月收治的心悸(室性早搏)痰火扰心证患者90例进行研究。按照随机数表法将患者分为两组各45例。对照组给予常规药物治疗,观察组给予黄连温胆汤加减治疗。于治疗一个月后观察比较两组患者的临床疗效,不良反应发生率,并比较治疗前后两组患者中医证候评分及室性早搏次数。结果:观察组总有效率明显高于对照组(86.67%vs 68.89%),差异有统计学意义(P<0.05);治疗后,观察组患者中医证候单项评分中,心悸[(1.91±0.32)分]、胸闷[(1.47±0.26)分]、气短[(0.87±0.15)分]、乏力[(0.74±0.17)分]、心烦[(0.33±0.07)分]、口干[(0.62±0.19)分]、失眠[(0.21±0.04)分]、脉象[(0.73±0.17)分]、舌象[(1.07±0.15)分]、纳差[(0.19±0.03)分]均明显低于对照组[(2.76±0.56)分、(2.26±0.51)分、(1.67±0.33)分、(1.68±0.26)分、(0.89±0.23)分、(0.96±0.31)分、(0.38±0.09)分、(1.04±0.29)分、(1.26±0.26)分、(0.33±0.06)分],差异有统计学意义(P<0.05);观察组患者治疗后室性早搏次数[(1290.00±210.10)次]明显少于对照组[(3112.80±280.20)次],差异有统计学意义(P<0.05)。结论:黄连温胆汤加减治疗心悸(室性早搏)痰火扰心证临床疗效显著,可促进患者中医证候的改善,减少室性早搏次数,安全性高,值得临床推广应用。 Objective: To explore the TCM syndrome improvement and prognosis of using Huanglian Wendan Decoction in the treatment of palpitation(ventricular premature beat) and phlegm fire disturbing heart syndrome, so as to provide basis for clinical treatment. Methods: 90 patients with palpitation(ventricular premature beat) and phlegm fire disturbing heart syndrome were selected from January 2018 to January 2020 in our hospital. The patients were randomly divided into two groups, 45 cases in each group. The controlled group was given conventional drug treatment, and then the observation group was given Huanglian Wendan Decoction. After one month of treatment, the clinical efficacy and incidence of adverse reactions were observed and compared between the two groups, and the TCM syndrome score and the number of premature ventricular contractions were compared between the two groups before and after treatment. Results: The total effective rate of the observation group was significantly higher than that of the controlled group(86.67% vs 68.89%),the difference was statistically significant(P<0.05). After treatment, palpitation [(1.91±0.32) score],chest tightness[(1.47±0.26) score],shortness of breath[(0.87±0.15) score],fatigue [(0.74±0.17) score],upset [(0.33±0.07) score],dry mouth [(0.62±0.19) score],insomnia [(0.21±0.04) score],pulse[(0.73±0.17) score],tongue [(1.07±0.26) score] and anorexia [(0.19±0.03)score] in the observation group were significantly lower than those in the controlled group[(2.76±0.56) score,(2.26±0.51) score,(1.67±0.33) score,(1.68±0.26) score,(0.89±0.23) score,(0.96±0.31) score,(0.38±0.09) score,(1.04±0.29) score,(1.26±0.26) score,(0.33±0.06) score],the difference was statistically significant(P<0.05). The number of ventricular premature beat after treatment in the observation group [(1290.00±210.10) times] was significantly less than that of the controlled group [(3112.80±280.20) times],the difference was statistically significant(P<0.05). Conclusion: Huanglian Wendan Decoction ha
作者 陈靖 肖珉 李攀 姚慧娟 丁杏婷 CHEN Jing;XIAO Min;LI Pan(Department of Cardiology,the First Peoples Hospital of Dongcheng District in Beijing,Beijing 100075,China;Department of Cardiology,Dongzhimen Hospital,Beijing University of Traditional Chinese Medicine,Beijing 100700.China)
出处 《四川中医》 2021年第1期54-57,共4页 Journal of Sichuan of Traditional Chinese Medicine
关键词 黄连温胆汤 心悸 痰火扰心证 中医证候 疗效 Huanglian Wendan Decoction Heart palpitations Phlegm-fire disturbing heart syndrome TCM syndromes Curative effect
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