摘要
目的:观察黄连温胆汤加减治疗痰热内扰型失眠患者的临床疗效。方法:选取2017年1月至2018年12月山东中医药大学附属医院收治的失眠患者60例作为研究对象,随机分为观察组和对照组,每组30例。观察组采用黄连温胆汤加减治疗,对照组给予舒乐安定,疗程4周。治疗后观察药物临床疗效及安全性,采用SDS、SAS、PSQI量表评价患者睡眠质量。结果:观察组总有效率90.0%;对照组总有效率83.3%,2组比较差异有统计学意义(P <0.05);2组治疗后SDS、SAS评分均明显降低,观察组改善更明显,2组比较差异有统计学意义(P <0.05),2组PSQI量表各项指标均较治疗前降低,观察组在睡眠质量、睡眠效率、睡眠障碍等方面较对照组改善更明显,差异有统计学意义(P <0.05)。结论:黄连温胆汤加减治疗痰热内扰型失眠具有较好的临床疗效。
Objective: To observe the clinical efficacy of Huanglian Wendan Decoction in treating patients with phlegm-heat internal disturbance. Methods: A total of 60 cases of insomnia patients admitted to the Affiliated Hospital of Shandong University of Traditional Chinese Medicine from January 2017 to December 2018 were selected as research objects and randomly divided into observation group and control group,with 30 cases in each group. The observation group was treated with Huanglian Wendan Decoction,and the control group was treated with Sulediazepam for 4 weeks. After treatment,the clinical efficacy and safety of the drugs were observed,and the sleep quality of the patients was evaluated by SDS,SAS and PSQI scales. Results: The total effective rate in the observation group was 90. 0%. The total effective rate of the control group was 83. 3%,and the difference between the two groups was statistically significant( P < 0. 05). 2 set of SDS and SAS scores were significantly lower after treatment,the observation group improved more obviously,two groups compare the difference was statistically significant( P < 0. 05),two groups of PSQI scale each index was decreased,the observation group in sleep quality,sleep efficiency,sleep disorder than that in control group improved more obviously,the difference was statistically significant( P < 0. 05). Conclusion: Huanglian Wendan Decoction has a good clinical effect in the treatment of phlegm-heat internal disturbance insomnia.
作者
陈晓燕
蔡治国
王康锋
CHEN Xiaoyan;CAI Zhiguo;WANG Kangfeng(Affiliated Hospital of Shandong University of Traditional Chinese Medicine,Jinan 250014,China)
出处
《世界睡眠医学杂志》
2020年第12期2064-2065,共2页
World Journal of Sleep Medicine
基金
山东省中医药科技发展计划项目(2015-083)。
关键词
失眠
痰热内扰
黄连温胆汤
治疗
Insomnia
Phlegm heat internal disturbance
Rhizoma Coptidis lukewarm gall soup
Treatment
