摘要
恶性黑色素瘤(malignant melanoma)是一种多发生于皮肤的高度恶性肿瘤,发病率正逐步升高,为皮肤的首位致死性疾病。常规的治疗方法包括手术、化疗、放疗、热疗及免疫治疗等。目前用于恶性黑色素瘤免疫和靶向治疗的药物包括细胞因子、激酶抑制剂、免疫检查点抑制剂等,本文对上述药物的应用、疗效及安全性等进行综述。
Malignant melanoma is a highly malignant tumor that often occurs in the skin,and its incidence is gradually increasing.It is the first fatal disease of the skin.Conventional treatment methods include surgery,chemotherapy,radiotherapy,hyperthermia and immunotherapy,etc.The drugs currently used for immune and targeted therapy of malignant melanoma include cytokines,kinase inhibitors,immune checkpoint inhibitors,etc.This article reviews the application,efficacy and safety of these drugs.
作者
严森林(综述)
赵颖海(审校)
YAN Sen-lin;ZHAO Ying-hai(Department of Pathology,Guangdong Medical University,Zhanjiang 524023,Guangdong,CHINA)
出处
《海南医学》
CAS
2021年第3期354-358,共5页
Hainan Medical Journal
基金
广东省湛江市第二批非资助科技攻关计划项目(编号:2015B01082)。
