摘要
使用基于纤维束示踪的空间统计学方法对原发性失眠患者的弥散张量成像影数据进行分析,探讨其大脑白质变化。结果显示相较于健康对照组,原发性失眠患者的白质连接发生改变,主要表现为前放射冠、胼胝体膝部的各向异性分数降低。进一步的相关分析结果表明胼胝体膝部区域各向异性分数值降低与患者睡眠状况自评量表分数显著负相关。
Tract-based spatial statistics was adopted to analyze the diffusion tensor imaging data of primary insomniacs(PI)with an aim to explore the changes in PI patients’white matter.Compared to the healthy control group,PI patients’white matter underwent successive changes,which were represented by the decrease of fractional anisotropy value in anterior corona radiata and in genu of corpus callosum.Moreover,a correlation analysis showed that the decreased fractional anisotropy value in genu of corpus callosum was negatively correlated with the scores of self-rating scale of sleep in PI patients.
作者
田时雨
薛婷
董芳
程永欣
崔永婷
谢东东
周弥
胡一婷
李晓健
黄若妍
王紫蕊
喻大华
TIAN Shiyu;XUE Ting;DONG Fang;CHENG Yongxin;CUI Yongting;XIE Dongdong;ZHOU Mi;HU Yiting;LI Xiaojian;HUANG Ruoyan;WANG Zirui;YU Dahua(School of Information Engineering,Inner Mongolia University of Science and Technology,Baotou 014010,China;School of Science,Inner Mongolia University of Science and Technology,Baotou 014010,China)
出处
《中国医学物理学杂志》
CSCD
2021年第1期51-53,共3页
Chinese Journal of Medical Physics
基金
国家自然科学基金(81571753,81571751,81871430,81871426,61771266,81401488)
内蒙古自治区高等学校青年科技英才支持计划(NJYT-17-B11)
内蒙古自然科学基金(2018LH08079,2019JQ07)。
