摘要
目的探讨脑白质疏松症(LA)患者睡眠障碍的影响因素。方法选择90例符合MRI诊断标准的LA患者(LA组)和90例性别、年龄相匹配的正常老年人(NC组)作为研究对象;通过询问病史调查血管危险因素,采用匹兹堡睡眠质量指数(PSQI)量表评定睡眠障碍情况,依据头颅MRI表现将LA组分为4个等级。结果 LA组高血压和糖尿病发生率显著高于NC组(P<0.05),LA组PSQI评分显著高于NC组(P<0.01)。LA组随着LA分级升高,PSQI评分依次增高(P<0.05)。回归分析显示,年龄、高血压、糖尿病、蒙特利尔认知评估量表等与LA患者睡眠障碍有关。结论LA患者存在睡眠障碍,与LA病变程度、认知损害、年龄、高血压、糖尿病等密切相关。
Objective To investigate the leukoaraiosis（LA）influencing factors of sleep disorder patients. Meth-ods 90 cases of LA patients which were conformed MRI diagnostic criteria were chosen as LA group,90 cases of normal old people which the gender and age were matched with LA group were chosen as NC group;by asking the medical history to inquirying blood vessel hazards;pittsburgh sleep quality index（PSQI）was adopted to evaluate the condition of sleep disorders,according to the performance MRI of skull to part LA group as four grades. Results In LA group,hypertension and diabetes incidence were significantly higher than that in group NC（P 〈 0. 05）;LA group,PSQI score was significantly higher than that of NC group（P 〈 0. 01）. LA group with the LA increasing grade,PSQI score increased（P 〈 0. 05）. Regression analysis showed that age,hypertension,diabetes and MoCA were associated with LA in patients with sleep disorders. Conclusion Patients with LA have a sleep disorder, which is closely related with the degree of cognitive impairment,LA lesions,age,hypertension,diabetes etc.
出处
《安徽医科大学学报》
CAS
北大核心
2015年第6期837-840,共4页
Acta Universitatis Medicinalis Anhui
基金
安徽高校省级自然科学基金重点项目(编号:KJ2011A170)
