摘要
目的探讨快速凝血检测仪与传统实验室方法(ACL-TOP750凝血分析仪)所检测国际标准化比值(INR)结果的一致性,评价快速凝血检测仪的准确性。方法选择2017年10月—2018年3月于本院口服抗凝药物(华法林)治疗的111例患者作为研究对象,分别用快速凝血检测仪与实验室标准检测方法(ACL-TOP750)两种方法检测INR值,对结果进行相关性(Pearson相关性分析)和偏倚度(Bland-Altman法)分析。结果快速凝血检测仪和ALC-TOP750的平均INR值为分别为(2.19±0.94)和(2.21±0.81);两种方法的相关性系数r为0.964(P<0.05);偏倚度为(0.06±0.23)。结论快速凝血检测仪与ACLTOP750法有很好的一致性,能够为口服抗凝药物患者特别是老年患者提供快速且可靠的INR监测。
Objective The paper is to evaluate the performance of rapid coagulometer detector by comparing its measured international standardized ratio(INR)with that measured by traditional laboratory method(ACL-TOP 750 coagulation analyzer),and to evaluate the accuracy of rapid coagulation detector.Methods We selected 111 patients as the study subjects,they were being treated with oral anticoagulants(warfarin)in the Second People's Hospital of Wuxi from October 2017 to March 2018.The INR values were detected by the two methods,and the results were analyzed by Pearson correlation analysis and Bland-Altman method.Results The mean INR values of rapid coagulometer detector and ALC-TOP 750 were(2.19±0.94)and(2.21±0.81),respectively.The correlation coefficients of the two methods were 0.964(P<0.05),and the bias was(0.06±0.23).Conclusions There was a good consistency between rapid coagulometer detector and standard laboratory method(ACL-TOP750).Rapid coagulometer detector could provide fast,reliable and accurate INR monitoring for patients having oral anticoagulants,especially for elderly patients.
作者
冉宝才
龚岚
冯秋婷
RAN Bao-cai(The second people's hospital of Wuxi afflilated to Nanjing Medical University,Wuxi,Jiangsu,21400,China)
出处
《齐齐哈尔医学院学报》
2020年第20期2538-2540,共3页
Journal of Qiqihar Medical University
基金
江苏省青年医学重点人才(QNRC2016142)。
关键词
国际标准化比值
口服抗凝治疗
华法林
International standardized ratio
Oral anti-coagulation therapy
Warfarin
