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伊立替康与替吉奥联合用药对晚期结肠癌患者的影响 被引量:1

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摘要 目的:探讨伊立替康与替吉奥联合用药对晚期结肠癌患者血清内癌胚抗原、糖链抗原50、糖链抗原199水平影响。方法:选取2018年4月~2019年4月收治的64例晚期结肠癌患者为研究对象,随机分为对照组和观察组,各32例。对照组给予FOLFIRI方案治疗,观察组给予伊立替康与替吉奥联合治疗,对比两组临床疗效、治疗前后血清内癌胚抗原、糖链抗原50、糖链抗原199水平和不良反应发生情况。结果:观察组部分缓解、疾病控制率分别为50.00%、84.38%,显著高于对照组的25.00%、56.25%(P<0.05);两组治疗后血清内癌胚抗原、糖链抗原50、糖链抗原199水平均较治疗前降低,且观察组低于对照组(P<0.05);两组不良反应发生率比较,差异无统计学意义(P>0.05)。结论:伊立替康与替吉奥联合治疗晚期结肠癌疗效满意,可显著降低患者血清内癌胚抗原、糖链抗原50、糖链抗原199水平。
出处 《实用中西医结合临床》 2020年第17期42-43,共2页 Practical Clinical Journal of Integrated Traditional Chinese and Western Medicine
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