摘要
随着人口老龄化的加剧,阿尔茨海默病发病率逐年攀升,西医疗法至今未有长期有效的治疗药物。中医药学对痴呆的认识载数千年,累积了丰富的临床经验和实用方剂。基于"肝肾同源"理论对阿尔茨海默病的中医治疗在多项临床报道中获得满意疗效。基于古代典籍和现代研究报道,从理论探讨、实验机制、临床研究分析"肝肾同源"理论与阿尔茨海默病的病因病机、治则治法的关联,为"肝肾同源"指导治疗阿尔茨海默病总结理论、实验、临床证据,提出基于该理论指导临床研究仍亟待深入挖掘的机制问题,旨在为临床中阿尔茨海默病的中医药防治方案提供理论参考和更广阔的治疗思路。
With aging of population, the incidence of senile dementia is increasing year by year. Yet there is no long-term effective drug for dementia therapy. Nevertheless, the accumulation of clinical experience and applicable formulae in traditional Chinese medicine offer a new sight for the therapy of senile dementia. Lots of TCM treatments based on the "homogeny of liver and kidney" theory are reported effective in therapy of senile dementia. On the basis of ancient classics and modern researches, the inner theories, experimental mechanisms and clinical analyses involved in the "homogeny of liver and kidney" theory and the dementia therapy were discussed in this paper. The academic, experimental and clinical evidences for dementia therapy based on the "homogeny of liver and kidney" theory were summarized and the uncovered mechanisms were brought out to be further studied, in order to provide practical references and broader thoughts for TCM prevention in the therapy of senile dementia.
作者
杨玉芳
何建成
YANG Yufang;HE Jiancheng(Shanghai University of Traditional Chinese Medicine,Shanghai 201203,China)
出处
《中华中医药学刊》
CAS
北大核心
2020年第12期52-54,共3页
Chinese Archives of Traditional Chinese Medicine
基金
国家自然科学基金面上项目(81573899)
中国博士后科学基金面上项目(2019M651562)
上海市青年科技扬帆英才计划(19YF1448500)。
关键词
阿尔茨海默病
肝肾同源
病因病机
治则治法
临床参考
senile dementia
homogeny of liver and kidney
etiology and pathogenesis
treatment principle and method
practical reference
