摘要
目的:明确肾功能不全对急诊科患者肌钙蛋白(cTnT)、N-端脑钠肽前体(NT-proBNP)水平的影响。方法:选取2019年1-9月急诊科非心源性因素cTnT>40 ng/L的患者203例,通过估算肾小球滤过率(eGFR)将患者分为4组。研究cTnT、NT-proBNP与eGFR的关系。结果:203例患者中,平均年龄(69±17)岁,男性119例(58.6%);eGFR<30 mL/(min·1.73 m2)组cTnT、NT-proBNP水平高于eGFR≥60 mL/(min·1.73 m2)组,差异有统计学意义(P<0.05);eGFR 30~60 mL/(min·1.73 m2)组NT-proBNP水平高于eGFR≥60 mL/(min·1.73m2)组,差异有统计学意义(P<0.05)。结论:急诊患者cTnT和NT-proBNP水平随着eGFR水平的下降而升高,重度肾功能不全患者升高明显。
Objective:To clarify the effect of renal insufficiency on the cTnT and NT-proBNP levels of emergency patients.Methods:From January to September 2019,203 cases of patients with non-cardiogenic factors and cTnT>40 ng/L were enrolled,they were divided into 4 groups by estimating glomerular filtration rate(eGFR),the relationship between cTnT,NT-proBNP and eGFR was researched.Results:Of 203 participants,the mean age was(69±17)years old and the male was 119(58.6%).CTnT and NT-proBNP in the eGFR<30 mL/(min·1.73 m2)group were higher than that in the eGFR≥60 mL/(min·1.73 m2)group,the difference was statistically significant(P<0.05).NT-proBNP in the eGFR 30~60 mL/(min·1.73 m2)group was higher than that of eGFR≥60 mL/(min·1.73 m2)group,the difference was statistically significant(P<0.05).Conclusion:The levels of cTnT and NT-proBNP in emergency patients increase with the decrease of eGFR level and patients with severe renal insufficiency increase significantly.
作者
曾朝涛
王鹏飞
黄云苑
Zeng Chaotao;Wang Pengfei;Huang Yunyuan(Department of Emergency,Sun Yat-Sen Memorial Hospital of Sun Yat-sen University,Guangzhou Province,Guangdong Guangzhou 510120)
出处
《中国社区医师》
2020年第35期14-15,共2页
Chinese Community Doctors
