摘要
以超声波辐射法,用醇、胺为原料,分别与酰氯通过酯化和酰化反应,在室温下高效合成了28种桥联型(双、三、四)芳基羧酸衍生物.并通过红外、核磁共振、质谱、元素分析等手段对产物进行结构表征.结果表明:该超声波辐射方法反应时间短,反应产率高,条件温和,无需使用催化剂,属于绿色合成,是合成芳基羧酸衍生物的一种新型通用方法.
Ultrasonic radiation was applied to perform the esterification and acylation reaction of alcohols and amines with acid chlorides.28 bridged(bis-,tri-and tetra-)aryl carboxyl derivatives were synthesized at room temperature,with the structures characterized by IR,1H NMR,MS,elemental analysis and so forth.The results indicated that the reactions were accomplished with high yield in short reaction time under mild conditions,and with no use of catalyst.This green approach represents a new general route for the synthesis of aryl carboxylic acid derivatives.
作者
陈连清
杨耕涛
伍超
CHEN Lianqing;YANG Gengtao;WU Chao(Hubei Key Laboratory of Catalysis and Materials Science,College of Chemistry and Materials Science,South-Central University for Nationalities, Wuhan 430074, China)
出处
《中南民族大学学报（自然科学版）》
CAS
2020年第6期551-563,共13页
Journal of South-Central University for Nationalities：Natural Science Edition
基金
国家自然科学基金资助项目(31402137)
人事部留学人员科技活动择优资助项目(BZY13007)
湖北省杰出青年基金资助项目(2013CFA034)
湖北省青年英才开发计划(RCJH15001)。
