摘要
目的探究内镜黏膜下切除术及内镜黏膜下剥离术对早期胃癌的治疗效果,并对其安全性进行评估。方法选择80例早期胃癌患者为研究对象,按照其选择术式的差异将其分为实验组与对照组,每组40例。对照组患者接受内镜黏膜下切除术,实验组患者接受内镜黏膜下剥离术,对比2组患者切除效果、手术时间、术中出血量、住院时间、术后各类并发症发生率,并对2组患者实施为期12个月的术后随访,对比2组患者术后复发率。结果(1)2组患者整块切除、R0切除和R1切除率对比差异不具有统计学意义(P>0.05)。(2)实验组患者手术事件、术中出血量、住院时间均低于对照组患者,差异具有统计学意义(P<0.05)。(3)术后并发症发生率实验组显著低于对照组,差异具有统计学意义(P<0.05)。(4)2组患者术后复发率相比,差异不具有统计学意义(P>0.05)。结论内镜黏膜下切除术及内镜黏膜下剥离术对早期胃癌均具有较好的治疗效果,但内镜黏膜下剥离术手术指标更优异,患者术后并发症发生率更低。
Objective To investigate the therapeutic effect of endoscopic submucosal resection and endoscopic submucosal dissection on early gastric cancer,and to evaluate the safety.Methods 80 patients with early gastric cancer were selected as the research objects,and they were divided into the experimental group and the control group according to the difference of their choice of surgical procedures,with 40 cases in each group.The control group patients underwent endoscopic submucosal resection,the experimental group patients underwent endoscopic submucosal dissection,and the resection effect,operation time,intraoperative blood loss,hospital stay,and various postoperative complications were compared between the 2 groups.The 2 groups of patients were followed up for a period of 12 months,and the postoperative recurrence rate was compared between the 2 groups.Results(1)There was no statistically significant difference in the rates of mass resection,R0 resection,and R1 resection between the 2 groups of patients(P>0.05);(2)The surgical events,intraoperative blood loss,and length of hospital stay in the experimental group were lower than the control group,The difference was statistically significant(P<0.05);(3)The incidence of postoperative complications in the experimental group was significantly higher than that in the control group,and the difference was statistically significant(P<0.05);(4)The difference in postoperative recurrence rate between the 2 groups was not statistically significant(P>0.05).Conclusion Endoscopic submucosal dissection have better therapeutic effects on early gastric cancer,but the comparison shows that the surgical indicators of endoscopic mucosal dissection are better and the incidence of postoperative complications is lower.
作者
夏永欣
方玲
张萌
张向东
XIA Yongxin;FANG Ling;ZHANG Meng(Nanyang Central Hospital,Nanyang,473000)
出处
《实用癌症杂志》
2020年第12期2032-2034,2063,共4页
The Practical Journal of Cancer
关键词
内镜黏膜下切除术
内镜黏膜下剥离术
早期胃癌
临床疗效
安全性
Endoscopic submucosal resection
Endoscopic submucosal dissection
Early gastric cancer
Clinical efficacy
Safety
