摘要
目的探讨胰腺实性假乳头状肿瘤(SPN)的临床病理特点、诊治及预后情况。方法收集2010年10月至2019年10月16例SPN患.者的临床资料,回顾性分析其临床特点、辅助检查、治疗方式及病理资料,并进行随访。结果16例患者中男2例,女14例;年龄15~56岁,10例肿瘤体积较小者无明显临床症状,6例肿瘤体积较大者临床表现主要为腹痛,影像学检查以囊实性混合或实性占位为主,伴不同程度钙化。16位患者均进行手术切除治疗,术后行病理形态学及免疫组化检查证实均为SPN,未见淋巴结转移,术后恢复情况良好,随访无复发。结论SPN是一种罕见肿瘤并好发于年轻女性,临床表现缺乏特异性,血生化及肿瘤指标可无明显异常,影像学在其诊断中发挥重要作用,病理形态及分子生物学标记物具有一定特异性,手术切除是其最佳治疗方式。
Objective To investigate the clinicopathologic features,dignosis,treatment and prognosis of solid pseudopaillary neoplasm of the pancreas(SPN).Methods 16 SPN patients treated in our hospital from October 2010 to October 2019 were collected,and the clinical features,auxilary examination,treatment and pathological data were analyzed retrospectively.All the patients were followed-up.Results Of the 16 patients,2 were male and 14 were female,aged 15-56.10 patients with small tumor size had no obvious clinical symptoms,while the other 6 patients with large tumor size had abdominal pain.The imageological examination showed cystic mixed solid,or solid mass,with varying degrees of calcification.All the patients underwent surgical resection.All of them were confrmed SPN by pathomorphology and immunohistochemistry detection without metastasis in lymph nodes.The postoperative recovery was good and no recurrence was found during follow-up.Conclusion SPN is a rare tumor that tends to afct young females.Its clinical manifesations,blood biochemistry and tumor markers are lack of specifcity.Imageological examination plays an important role in its diagnosis,besides,pathological morphology and molecular biological markers also have some specifcity.Furthermore sungical resection is the best treatment for SPN.
出处
《浙江临床医学》
2020年第11期1648-1650,共3页
Zhejiang Clinical Medical Journal
关键词
胰腺实性假乳头状肿瘤
影像学检查
病理
免疫组化
手术切除
Solid pseudopaillary neoplasm
Imageological examinaion
Pathology
Immunohistochemistry
Surgical resccioh
Follow-up
