摘要
目的研究中年男性慢性肾功能不全患者性功能障碍的危险因素。方法选取2016年6月至2019年6月岳池县人民医院肾内科收治的80例中年男性慢性肾功能不全患者作为研究对象。根据患者有无性功能障碍分为观察组(有性功能障碍,n=59)和对照组(无性功能障碍,n=21)。收集两组患者的一般临床数据,检测血生化水平及激素水平,Logistic多因素回归分析患者性功能障的危险因素。结果80例患者仅21例无性功能障碍,59例有性功能障碍,发病率达73.75%。观察组患者中轻度性功能障碍16例(27.12%),中度性功能障碍21例(35.59%),重度性功能障碍22例(37.29%);表现出勃起障碍、性欲下降、性交疼痛、射精困难/早泄、性高潮障碍等不同表现。观察组患者年龄、有吸烟史及糖尿病史的比例、抑郁状态患者比例、血肌酐水平均明显高于对照组,甲状旁腺激素(PTH)水平明显低于对照组,差异具有统计学意义(P<0.05)。且Logistic回归分析发现,高龄、有吸烟史、有糖尿病史、抑郁状态、高血肌酐水平、低PTH水平均为性功能障碍的独立危险因素。结论本研究中,中年男性慢性肾功能不全患者中有73.75%出现性功能障碍,患者的年龄增高、有吸烟史、有糖尿病史、抑郁、血清肌酐水平升高、PTH水平下降等均易导致性功能障碍。
Objective To study the epidemiology and risk factors of sexual dysfunction in middle-aged men with chronic renal insufficiency.Methods A total of 80 middle-aged male patients with chronic renal insufficiency admitted to the Department of Nephrology,Yuechi County People's Hospital from June 2016 to June 2019 were selected as the research objects.According to whether the patients had sexual dysfunction,they were divided into observation group(sexual dysfunction,n=59)and control group(non-sexual dysfunction,n=21).General clinical data of the two groups were collected,blood biochemical level and hormone level were measured,and risk factors of sexual dysfunction were analyzed by Logistic multivariate regression analysis.Results Of the 80 patients,21 hadn't sexual dysfunction and 59 had sexual dysfunction,with an incidence of 73.75%.In the observation group,there were 16 cases of mild sexual dysfunction(27.12%),21 cases of moderate sexual dysfunction(35.59%)and 22 cases of severe sexual dysfunction(37.29%).The symptoms includes erectile dysfunction,decreased libido,painful sexual intercourse,ejaculation difficulty/premature ejaculation,orgasmic disorder,etc..Age,proportion of patients with smoking history and diabetes history,proportion of patients with depression status and serum creatinine level in the observation group were significantly higher than those in the control group,and PTH level was significantly lower than that in the control group,with statistically significant differences(P<0.05).Logistic regression analysis found that advanced age,smoking history,diabetes history,depression status,high serum creatinine level and low PTH level were all independent risk factors for sexual dysfunction.Conclusions In this study,73.75%of the middle-aged male patients with chronic renal insufficiency developed sexual dysfunction,and the patients'age,smoking history,diabetes history,depression,increased serum creatinine level and decreased PTH level were independent risk factors for the disease.
作者
张勇林
张维明
屈明
ZHANG Yonglin;ZHANG Weiming;QU Ming(Department of Nephrology,Yuechi County People's Hospital,Guang'an 638300,Sichuan,China;Department of Nephrology,Guang'an People's Hospital,Guang'an 638500,Sichuan,China)
出处
《中国性科学》
2020年第11期14-16,共3页
Chinese Journal of Human Sexuality
