摘要
结节性痒疹(prurigo nodularis,PN)是一种治疗较困难、剧烈瘙痒的慢性皮肤病,临床常表现为高度角化,对称分布于四肢伸侧的瘙痒性丘疹和结节。对其发病机制的深刻认识,能丰富该病的治疗手段。顽固性瘙痒是影响患者生活质量的重要因素,目前已知其发病与免疫细胞、神经因素、汗腺功能、心理因素有关。本文就近几年相关发病机制的具体研究进展进行综述。
Prurigo nodularis is a kind of chronic skin disease that is difficult to treat and characterized by severe itching.It usually manifests as highly keratinized,itchy papules and nodules symmetrically distributed on the extremities of the limbs.A deep understanding of its pathogenesis can enrich the treatment methods of the disease.Refractory pruritus is an important factor affecting the quality of life of patients.It is currently known that its incidence is related to immune cells,neural factors,sweat gland function,and psychological factors.This article only summarizes the specific research progress of related pathogenesis in recent years as follows.
作者
钟婷
刘藕根
ZHONG Ting;LIU Ougen(Department of Dermatology,the Second Affiliated Hospital of Nanchang University,Nanchang 330006,China)
出处
《中国皮肤性病学杂志》
CAS
CSCD
北大核心
2020年第12期1453-1455,1459,共4页
The Chinese Journal of Dermatovenereology
基金
江西省教育厅一般项目(GJJ170093)。
关键词
结节性痒疹
发病机制
病理
Prurigo nodularis
Pathogenesis
Pathology
