摘要
目的研究缬沙坦联合螺内酯治疗急性前壁心肌梗死的效果。方法将60例急性前壁心肌梗死患者通过平均抽签法则分为观察组和对照组,每组30例,对照组单纯应用缬沙坦治疗,观察组通过缬沙坦联合螺内酯治疗。比较两组患者的治疗效果和心血管不良事件发生率。结果观察组治疗有效率为96.67%,对照组治疗有效率为73.33%,两组比较有统计学意义(P<0.05);观察组不良心血管事件发生率为6.67%,对照组为6.67%,两组比较无统计学意义(P>0.05)。结论对急性前壁心肌梗死患者选择缬沙坦联合螺内酯进行治疗能够提升治疗总有效率,降低心血管不良事件发生率。
Objective To study the eff ect of valsartan and spironolactone in the treatment of acute anterior myocardial infarction.Methods Sixty patients with acute anterior myocardial infarction were divided into observation group and control group by the avera ge lottery method,each with 30 cases.The control group was treated with valsartan alone,and the observation group was treated with valsartan combined with spironolactone.The treatment eff ect and the incidence of cardiovascular adverse events were compared between the two groups.Results The eff ective rate of treatment in the observation group was 96.67%,and the eff ective rate in the control group was 73.33%,which was statistically signifi cant(P<0.05);the incidence of adverse cardiovascular events in the observation group was 6.67%and that in the control group was 6.67%.The comparison between the two groups was not statistically signifi cant(P>0.05).Conclusion The choice of valsartan combined with spironolactone for the treatment of patients with acute anterior myocardial infarction can increase the total eff ective rate of treatment and reduce the incidence of cardiovascular adverse events.
作者
赵丽丽
ZHAO Lili(Central Hospital of Faku County,Shenyang 110400,China)
出处
《中国医药指南》
2020年第30期117-118,共2页
Guide of China Medicine
关键词
急性前壁心肌梗死
缬沙坦
螺内酯
Acute anterior myocardial infarction
Valsartan
Spironolactone