摘要
目的分析肺结核合并2型糖尿病患者治疗的过程中实施不同治疗方案对其临床疗效的影响。方法本次试验研究选取76例肺结核合并2型糖尿病患者作为研究对象,其纳入的起止时间分别为2018年4月至2019年4月,采用1∶1随机分组原则将患者分为试验组与对比组,每组各有患者38例,试验组患者将胰岛素皮下注射作为降糖方案,对比组患者将口服降糖药物作为治疗方案,对比分析两组患者的临床疗效。结果治疗后试验组患者空腹、餐后2 h血糖、糖化血红蛋白水平均明显低于对比组(P<0.05),病灶吸收率、治疗有效率、痰菌转阴率、空洞闭合率均高于对比组(P<0.05)。结论在为肺结核合并2型糖尿病患者实施治疗的过程中不同降糖方案的治疗效果不尽相同,其中胰岛素皮下注射的治疗效果显著优于口服降糖药物,改善了患者空腹血糖、餐后2 h血糖以及糖化血红蛋白等指标,提高了痰菌转阴率和空洞闭合率,有助于患者治疗效果的提升与病情的更快恢复。
Objective To observe the eff ect of diff erent treatment options on the clinical effi cacy of patients with tuberculosis and type 2 diabetes during the course of treatment.Methods In this experimental study,76 patients with pulmonary tuberculosis and type 2 diabetes were selected as the research objects.The start and end times of their enrollment were April 2018 and April 2019 respectively.The patients were divided into experimental groups and comparison groups according to the 1∶1 randomization principle.There were 38 patients in each group.In the experimental group,insulin was injected subcutaneously as the hypoglycemic regimen,and the patients in the comparison group were treated with oral hypoglycemic drugs.The clinical effi cacy of the two groups was compared.Results After treatment,the blood glucose and glycosylated hemoglobin levels of the experimental group were signifi cantly lower than those of the comparison group(P<0.05),and the rate of absorption of lesions,eff ective rate of treatment,sputum conversion rate,and cavity closure rate were higher than those of the comparison group(P<0.05).Conclusion In the process of treating patients with tuberculosis and type 2 diabetes,the therapeutic eff ects of diff erent hypoglycemic regimens are not the same.Among them,the therapeutic eff ect of insulin subcutaneous injection is signifi cantly better than oral hypoglycemic drugs,which improves the fasting blood sugar and postprandial 2 hours blood sugar and glycosylated hemoglobin and other indicators increase the rate of sputum bacteria conversion and the rate of cavity closure,which is helpful to improve the treatment eff ect and faster recovery of patients.
作者
季微微
JI Weiwei(Chest Hospital of Liaoyuan City,Liaoyuan 136200,China)
出处
《中国医药指南》
2020年第30期69-70,共2页
Guide of China Medicine
关键词
肺结核
2型糖尿病
不同降糖方案
胰岛素皮下注射
口服降糖药物
Tuberculosis
Type 2 diabetes
Diff erent hypoglycemic regimens
Insulin subcutaneous injection
Oral hypoglycemic drugs
