摘要
目的探讨影响儿童支气管哮喘吸入糖皮质激素(ICS)治疗依从性的影响因素。方法收集2018年8月至2019年8月天津市儿童医院150例支气管哮喘患儿,收集资料包括年龄、性别。以家长对哮喘的认识和对ICS副作用的认识、家长受教育程度、用药频率、疾病严重程度、ICS种类作为可能的影响因素,并进行多因素分析。结果患儿ICS治疗依从性发生率为37.3%。单因素分析显示:依从性差组与依从性好组相比,儿童年龄大,用药频率高,家长对哮喘的认识差,家长对ICS副作用的认识多(P<0.05)。应用logistic进行多因素分析显示:年龄大,家长对ICS副作用的认识多,用药频率高(>1次)为独立危险因素(P<0.05)。结论儿童年龄越大,家长对ICS副作用的不正确认识越多,每日用药频率高均可导致儿童支气管哮喘ICS治疗依从性下降。
Objective To explore the influencing factors of inhaled glucocorticoids(ICS)therapy compliance in children with bronchial asthma.Methods A total of 150 patients with bronchial asthma were collected from August 2018 to August 2019 in Tianjin Children’s Hospital.Clinical data of the subjects included age and gender.The understanding of asthma and the side effects of inhaled glucocorticoids,the educational level of parents,frequency of medication,severity of disease and types of ICS were taken as possible influencing factors,and multi-factor analysis was conducted.Results The incidence of inhaled glucocorticoid therapy compliance was 37.3%.Compared with the good compliance group,the children in the poor compliance group were older,the medication frequency was higher,their parents had poor awareness of asthma and more awareness of the side effects of ICS by single factor analysis(P<0.05).Logistic multivariate analysis showed that older age,parents’awareness of the side effects of ICS and the high frequency of medication(>1)were independent risk factors(P<0.05).Conclusion The older children,the more incorrect understanding of the side effects of inhaled glucocorticoids by parents,and the high frequency of medication may lead to decreased compliance of inhaled glucocorticoids in children with bronchial asthma.
作者
肖亚男
XIAO Ya-nan(Pharmacy Department,Tianjin Children’s Hosptial(Tianjin University Children’s Hospital),Tianjin 300074,China)
出处
《河南医学研究》
CAS
2020年第32期5983-5986,共4页
Henan Medical Research
关键词
支气管哮喘
儿童
吸入糖皮质激素
治疗依从性
bronchial asthma
children
inhaled glucocorticoids
therapy compliance
