摘要
随着对创面愈合机制逐渐深入认识,创面微环境的概念与构成不断完善与清晰。在创面愈合进程中,外部微环境和内部微环境既相对独立,又交互影响,始终处于动态变化之中。需要从空间、时间等多维度认清创面愈合的微环境变化规律与特点,才可能根据具体情况有目的地调控创面愈合进程,有助于在合适的时间窗采取合理的再生医学技术,实现皮肤软组织损伤真正意义上的完美修复与再生。
With gradually in-depth understanding of wound healing mechanism,the concept and composition of wound microenvironment have been improved and clarified.In the process of wound healing,the external microenvironment and internal microenvironment are both relatively independent and interact with each other,and are always in dynamic change.It is necessary to understand the changing rules and characteristics of wound healing microenvironment from multiple dimensions,such as space and time,so that the process of wound healing can be purposefully regulated and controlled depending on actual circumstance.It helps the adoption of reasonable regenerative medicine technology at the proper time window to realize perfect repair and regeneration after skin and soft tissue injury in the true sense.
作者
程飚
付小兵
Cheng Biao;Fu Xiaobing(Department of Burns and Plastic Surgery,General Hospital of Southern Theater Command of PLA,Guangzhou 510010,China;Research Center for Wound Repair and Regeneration,Medical Innovation Research Department,the PLA General Hospital,Beijing 100048,China)
出处
《中华烧伤杂志》
CAS
CSCD
北大核心
2020年第11期1003-1008,共6页
Chinese Journal of Burns
基金
国家重点研发计划(2017YFC1103301)
国家自然科学基金面上项目(81671924)
军事医学创新工程专项(18CXZ029)。
关键词
伤口愈合
再生
微环境
创面
修复
Wound healing
Regeneration
Microenvironment
Wound
Repair
