摘要
目的:探讨宣城地区幽门螺杆菌(Hp)感染胃黏膜病变临床病理组织类型临床特征。方法:回顾性研究医院消化内镜中心检查5125例患者胃黏膜病变送病理检查确诊Hp感染的临床资料(Hp病理检查5390处),分Hp(+)和Hp(-)组,分析两组与胃黏膜病变不同病理组织类型关系。结果:Hp(+)组1478例(27.42%)、Hp(-)组3912例(72.58%),两组病理类型特征比较,差异有统计学意义(P<0.05)。结论:Hp与胃黏膜病变病理组织类型中黏膜慢性炎伴活动、黏膜慢性炎伴活动、肠上皮化生关系密切,多见于胃黏膜病变中胃糜烂及溃疡,Hp感染增加胃黏膜病变的损伤、炎症活动和肠上皮化生的发生率,发生胃早癌的风险明显增加。
Objective:To analyze the clinical characteristic of pathological type of gastric mucosal lesion which affected Helicobactor Pylori in Xuancheng area.Methods:Retrospectively analyze the clinical data of 5125 patients with gastric mucosal lesion diagnosed Helicobactor Pylori infection by pathological examination in digestive endoscopy center of Xuancheng People,s Hospital(There were 5390 cases with pathological examination).These patients were divided into Helicobactor Pylori positive group and Helicobactor Pylori negative group.To analyze the relationship between the two groups and different pathological types of gastric mucosal lesions.Results:There were 1478 cases in Helicobactor Pylori positive group(27.42%),and 3912 cases in Helicobactor Pylori negative group(72.58%).Comparision of pathological type characteristics between two groups,there were statistical difference(P<0.05).Conclusion:Helicobactor Pylori was closely related to chronic inflammation of gastric mucosa with activity and intestinal metaplasia.Gastric erosion and ulcer of gastric mucosal lesion were most commonly seen.Helicobacter Pylori infection increased the incidence of gastric mucosal lesion damage,inflammatory activity,intestinal metaplasia,and significantly increased the risk of early gastric cancer.
作者
邓衍部
黄志刚
周政
刘有理
贺道兴
韩圆圆
牛多山
DENG Yan-bu;HUANG Zhi-gang;ZHOU Zheng(The People's Hospital of Xuancheng,Xuancheng 242000,Anhui)
出处
《安徽卫生职业技术学院学报》
2020年第5期100-101,共2页
Journal of Anhui Health Vocational & Technical College
关键词
HP
胃黏膜病变
病理类型特征
helicobactor pylori
gastric mucosal lesion
pathological type characteristics
