摘要
目的通过观察颈椎病患者的局部疼痛阈值、5-羟色胺(5-HT)和肿瘤坏死因子-α(TNF-α)的变化,评价尺胫针结合体针疗法的临床效果。方法纳入2016年5月—2018年5月于陕西中医药大学附属医院骨科及康复医学科门诊及住院收治的符合纳入标准的颈椎病患者74例,按随机数字表法将其分为观察组(尺胫针结合体针治疗)和对照组(单纯采用体针治疗),各37例,观察并分析两组患者治疗前后的疼痛阈值、血浆中5-HT和TNF-α的含量。结果两组患者治疗后的疼痛阈值均有明显提高,且观察组高于对照组(P<0.05)。两组患者治疗后血浆中的5-HT和TNF-α含量均低于治疗前,且观察组低于对照组(P<0.05)。结论尺胫针结合体针疗法能显著提高颈椎病患者的疼痛阈值,其中的作用机制可能与降低血浆中5-HT和TNF-α含量有关。
Objective To observe the clinical effects of ulnar-tibial needle combined with body acupuncture on local pain threshold,plasma 5-hydroxytryptamin(5-HT)and tumor necrosis factor-α(TNF-α)in patients with cervical spondylosis and neck pain.Methods A total of 74 patients with cervical spondylosis who met the inclusion criteria treated in the outpatient and inpatient Department of Orthopedics and Rehabilitation Medicine in the Affiliated Hospital of Shaanxi University of Chinese Medicine,who met the inclusion criteria,were divided into the observation group(treated with ulnar-tibia needle combined with body acupuncture)and the control group(treated with body acupuncture alone)according to random table method,with 37 cases in each group.The pain threshold,plasma 5-HT and TNF-αlevels of patients in two groups were observed and analyzed before and after the treatment.Results The pain threshold of the two groups increased after treatment,and the observation group was higher than the control group(P<0.05).The levels of plasma 5-HT and TNF-αof the two groups were lower than those before treatment,and compared with the control group,the the observation group was lower than the control group(P<0.05).Conclusion The combination of ulnar-tibial needle and body acupuncture can significantly improve the pain threshold in patients with cervical spondylosis and neck pain.The mechanism of action may be related to the reduction of plasma 5-HT and TNF-α.
作者
张丽
刘宝玉
董博
ZHANG Li;LIU Baoyu;DONG Bo(Baoji Vocational and Technical Colledge,Shaanxi Province,Baoji721013,China;the Second Department of Orthopedics and Joint,Baoji Hospital of Traditional Chinese Medicine,Shaanxi Province,Baoji721013,China;Department of Bone Disease,Affiliated Hospital of Shaanxi University of Chinese Medicine,Shaanxi Province,Xianyang712000,China)
出处
《中国医药导报》
CAS
2020年第29期135-138,共4页
China Medical Herald
基金
全国中医临床特色技术传承人才培训项目(陕中医药函〔2019〕171号)
陕西中医药大学学科创新团队项目(2019-YL02)。
关键词
尺胫针
电针
颈椎病
疼痛阈值
5-羟色胺
肿瘤坏死因子-Α
Ulnar-tibial needle
Electroacupuncture
Cervical spondylosis
Pain threshold
5-hydroxytryptamin
Tumor necrosis factor-α
