摘要
目的探讨益气活血法配合西医治疗气虚血瘀证陈旧性心肌梗死患者疗效及对生活质量的影响。方法将2017年1月—2018年6月在邯郸明仁医院治疗的78例气虚血瘀证陈旧性心肌梗死患者随机分为2组,对照组38例给予阿司匹林、单硝酸异山梨酯片、辛伐他汀、依那普利及倍他乐克治疗,观察组38例于对照组治疗基础上给予益气活血法治疗,观察2组治疗前及治疗12周后血液流变学、心功能、生活质量指标水平变化情况,统计2组疗效及不良反应发生情况。结果与治疗前比较,2组治疗后全血比黏度、血浆比黏度、全血还原黏度、纤维蛋白原、血细胞比容、左室舒张末径(LVDED)、左室收缩末径(LVSED)均明显降低(P均<0.05),左室射血分数(LVEF)、心排血量(CO)、每搏量(SV)及生活质量各项评分均明显升高(P均<0.05),治疗后观察组上述各指标改善情况均明显优于对照组(P<0.05);观察组和对照组治疗后总有效率分别为97.4%(38/39)和76.9%(30/39),观察组总有效率明显高于对照组(P<0.05);观察组和对照组不良反应发生率分别为5.2%(2/39)和2.6%(1/39),2组不良反应发生率比较差异无统计学意义(P>0.05)。结论益气活血法联合西医治疗气虚血瘀证陈旧性心肌梗死患者疗效较佳,可以显著改善心功能、血液流变学,并可以提高患者生活质量。
Objective It is to investigate the curative effect of treatment of replenishing Qi and activating blood combined with western medicine in patients with old myocardial infarction with Qi-deficiency and blood-stasis syndrome and its influence on their quality of life.Methods 78 patients with old myocardial infarction with Qi deficiency and blood stasis syndrome treated in Handan Mingren Hospital from January 2017 to June 2018 were randomly divided into 2 groups.38 patients in the control group were treated with aspirin,isosorbide mononitrate tablets,simvastatin,enalapril and betaloc,38 cases in the observation group were treated with the method of replenishing qi and activating blood on the basis of the control group.The changes of the blood rheology,cardiac function and quality of life before and after 12 weeks of treatment were observed in the two groups,the curative effect and the occurrence of adverse reactions were evaluated in the two groups.Results Compared with before treatment,the whole blood specific viscosity,plasma specific viscosity,whole blood reduced viscosity,fibrinogen,hematocrit,left ventricular end diastolic diameter(LVDED),left ventricular end systolic diameter(LVSED)were significantly reduced after treatment(P<0.05),and left ventricular ejection fraction(LVEF),cardiac output(CO),stroke volume(SV),and the scores of each item of quality of life were significantly increased(P<0.05),the improvement of the above indicators in the observation group was significantly better than that of the control group after treatment(P<0.05).The total effective rates of the observation group and the control group after treatment were 97.4%(38/39)and 76.9%(30/39),respectively,the observation group was obviously higher than the control group(P<0.05);the incidence of adverse reactions in the observation group and control group was 5.2%(2/39)and 2.6%(1/39),respectively,there was no significant difference in the incidence of adverse reactions between the two groups(P>0.05).Conclusion The method of replenishing Qi and ac
作者
秦浩玲
马会
梁书丽
马红莉
QIN Haoling;MA Hui;LIANG Shuli;MA Hongli(Handan Mingren Hospital, Handan 056000, Hebei, China;The First People’s Hospital of Wu’an City, Wu’an 056300, Hebei,China)
出处
《现代中西医结合杂志》
CAS
2020年第31期3456-3459,3503,共5页
Modern Journal of Integrated Traditional Chinese and Western Medicine
基金
河北省中医药管理局科研计划项目(2019396)。
关键词
益气活血法
阿司匹林
单硝酸异山梨酯
陈旧性心肌梗死
生活质量
method of replenishing Qi and activating blood
aspirin
isosorbide mononitrate
old myocardial infarction
quality of life
