期刊文献+

医用无定形磷酸钙3D打印液固作用过程分析

Analysis of liquid-solid interaction during three-dimensional printing of medical amorphous calcium phosphate
下载PDF
导出
摘要 背景:无定形磷酸钙具备优良的水化硬化特性,只需利用纯水作为粘接溶液即可打印成型,更重要的是打印骨成品无需进行高温烧结即可直接医学临床应用,故而非常契合3D打印技术的特性。目的:通过3D打印方式制备力学性能和打印精度满足实际应用需求的无定形磷酸钙骨修复材料。方法:通过共沉淀法制备无定形磷酸钙粉末,将其作为打印粉末材料;然后分别使用增稠剂和流平剂调节纯水的黏度和表面张力,并以其作为粘接溶液,通过3D打印机制取骨修复材料,研究粘接溶液的黏度和表面张力对液滴成形、液固交互作用、骨成品力学性能和打印精度的影响规律。结果与结论:通过考察液滴成形、液滴/无定形磷酸钙粉末交互作用等过程,获得粘接溶液最佳物化参数:黏度为8.0×10-3 Pa·s,表面张力为40.0×10-3 N/m,其不仅可稳定可控地形成液滴(Z=5.06),而且点阵喷洒时平稳地冲击粉末层(K=14.29),然后均匀顺利地渗入粉末层并及时铺展(We=36.86)。由此所制取的打印骨成品的力学性能较好(抗压强度为30.4 MPa),而且打印精度较高(成型误差为0.9 mm),同时孔隙数量较多(表明骨传导性较好),较大程度地满足了骨修复材料各种需求。 BACKGROUND:Based on excellent hydration ability,the materials for repairing bone defects could be fabricated by three-dimensional printing from amorphous calcium phosphate simply with pure water as adhesive solution;and more importantly,the printed products could be directly used in clinical medicine without high temperature sintering,so amorphous calcium phosphate fits well with technical features of three-dimensional printing.OBJECTIVE:To prepare bone repair materials of amorphous calcium phosphate with mechanical property and printing accuracy to meet practical application requirements by three-dimensional printing.METHODS:Amorphous calcium phosphate used as prototyping powder was prepared by coprecipitation method,and then the viscosity and surface tension of the deionized water as adhesive solution were adjusted by thickening agent and leveling agent,respectively.Afterwards,the three-dimensional printing productions for repairing bone defects were fabricated,and the effects of the viscosity and surface tension of adhesive solution on the forming of droplet,liquid-solid interaction and the mechanical property as well as printing accuracy of three-dimensional printing productions were investigated.RESULTS AND CONCLUSION:By investigating the forming of droplet and liquid-solid interaction,the optimal physicochemical parameters of the adhesive solution were obtained.The viscosity and surface tension of the optimal adhesive solution were 8.0×10-3 Pa·s and 40.0×10-3 N/m separately,and at this point,not only droplet could form stably and controllably(Z=5.06),but also it smoothly struck the powder layer during spraying(K=14.29),and then it infiltrated into the powder layer uniformly and spread in time(We=36.86).The corresponding three-dimensional printing production has good mechanical properties(compressive strength is 30.4 MPa),high printing accuracy(forming error is 0.9 mm),and a large number of pores indicating good bone conductivity,which partially meets clinical demands of repairing bone defects.
作者 聂建华 程江 莫嘉琪 Nie Jianhua;Cheng Jiang;Mo Jiaqi(Zhongshan Polytechnic,Zhongshan 528404,Guangdong Province,China;School of Chemistry and Chemical Engineering,South China University of Technology,Guangzhou 510640,Guangdong Province,China)
出处 《中国组织工程研究》 CAS 北大核心 2021年第16期2548-2553,共6页 Chinese Journal of Tissue Engineering Research
基金 广东省科技创新战略“攀登计划”专项资金(pdjh2020b1286),项目负责人:聂建华 中山市社会公益科技研究项目(2019B2062),项目负责人:聂建华 校级重点科研项目(2019KQ01),项目负责人:聂建华 校级青年科研骨干项目(2019GG03),项目负责人:聂建华。
关键词 材料 三维打印 粉末材料 粘接溶液 无定形磷酸钙 bone material three-dimensional printing powder material adhesive solution amorphous calcium phosphate
  • 相关文献

参考文献6

二级参考文献48

共引文献75

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部