摘要
目的:分析近10年老年多重用药的研究现状与热点前沿,为我国老年多重用药的研究提供参考。方法:检索2010年1月1日-2019年12月31日Web of Science数据库中核心数据库收录的老年多重用药相关的文献,采用CiteSpace 5.6.R5软件对发文量、作者、国家/地区、机构、期刊共被引情况、文献共被引情况进行分析,对关键词进行共现分析、聚类分析及突现(Burst)分析,绘制可视化图谱并分析结果。结果:共纳入文献3 521篇,老年多重用药研究的发文量整体呈上升趋势,高产作者主要以Bell JS和Hilmer SN为代表,均发表36篇,占总发文量的1.02%。美国(929篇,26.3%)和澳大利亚悉尼大学(101篇,2.87%)分别是发表文献最高产的国家和机构。Journal of the American Geriatrics Society是收录文章最多的期刊(2 202篇)。文献共被引频次最高是Radcliff S等在2015年发表的对Beers标准进行更新以用于减少潜在不适当用药的研究;文献共被引中心度最高是Spinewine A等在2007年发表的如何优化老年人处方的研究;关键词出现次数较多的包括老年人、多重用药、危险因素,中心度排名较高的包括生活质量、多重用药、Beers标准,目前研究的热点包括危险因素、结局指标以及对多重用药的减少策略;形成Breast cancer、Prescription、Disorder、Schizophrenia、Medication adherence、Trial等6个聚类;研究前沿是并发症、痛苦、老年衰弱、健康相关质量、认知障碍。结论:近10年来老年多重用药的研究日趋受到学者的重视,美国以及澳大利亚在该领域的贡献较大;研究主要集中在多重用药对健康结局的影响以及减少多重用药的策略上;未来可能会更多关注于多重用药对老年心理和认知、衰弱的相关研究。
OBJECTIVE:To analyze the research status and hotspot frontier of polypharmacy in the elderly in recent ten years,and to provide reference for polypharmacy study in the elderly in China.METHODS:The related literatures about polypharmacy in the elderly were retireved from Web of Science core database during Jan.1 st,2010-Dec.31 th,2019.CiteSpace 5.6.R5 software was used to analyze the quantity of pulished literatures,authors,country/area,institution,co-citation of journals and literatures.The keywords were taken as nodes for co-occurrence analysis,cluster analysis and Burst analysis,the visual maps were drawn and the results were analyzed.RESULTS:A total of 3521 literatures were included,and the quantity of published literatures about polypharmacy in the elderly was on the rise;high-yield authors mainly were Bell JS and Hilmer SN which were the representative with 36 papers published,accounting for 1.02%of the total.America(929 literaturesm 26.3%)and University of Sydney(101 literatures,2.87%)were the most high-yield country and institution respectively;Journal of the American Geriatrics Society was the journal with the most articles(2202 pieces).The most frequently cited literature was those published by Radcliff S team in2015 to update Beers standard to reduce potential inappropriate drug use;the research on how to optimize the prescription for the elderly published by Spinewine A team in 2007 had the highest co-citation centrality.The hot keywords were elderly,polypharmacy and risk factor;keywords with high centrality included quality of life,polypharmacy and Beers standard.Research hotspots included risk factor,outcome index and reduction strategy for polypharmacy.Six clusters were formed,including Breast cancer,Prescription,Disorder,Schizophrenia,Mediation attachment and Trial;complications,pain,frailty,health-related quality,intellectual disability were at the forefront of research.CONCLUSIONS:In the past 10 years,the research on polypharmacy in the elderly has been paid more and more attention by scholars;th
作者
渠吉皊
沈易静
周婷
刘永兵
QU Jiling;SHEN Yijing;ZHOU Ting;LIU Yongbing(School of Nursing,Yangzhou University,Jiangsu Yangzhou 225000,China)
出处
《中国药房》
CAS
北大核心
2020年第21期2664-2671,共8页
China Pharmacy
基金
新疆维吾尔自治区自然科学基金资助项目(No.2013211A059)。
