摘要
目的探讨明胶海绵联合Embosphere微球栓塞治疗肝癌破裂出血的效果。方法根据术中栓塞方法的不同将85例行经导管动脉栓塞术(TAE)的肝癌破裂出血患者分为明胶海绵组(n=39)和明胶海绵联合Embosphere微球组(n=46),比较两组患者的治疗效果。结果术后,两组患者的心率、收缩压、舒张压比较,差异均无统计学意义(P﹥0.05);明胶海绵联合Embosphere微球组患者的血红蛋白(Hb)水平高于明胶海绵组(P﹤0.05)。明胶海绵联合Embosphere微球组患者的输血量少于明胶海绵组,7 d内再出血率低于明胶海绵组(P﹤0.05)。术后,明胶海绵联合Embosphere微球组患者的谷丙转氨酶(ALT)、谷草转氨酶(AST)、总胆红素(TBil)水平均明显低于明胶海绵组,清蛋白(Alb)水平明显高于明胶海绵组(P﹤0.01)。结论明胶海绵联合Embosphere微球栓塞治疗肝癌破裂出血的临床效果良好。
Objective To explore the effect of gelatin sponge combined Embosphere microspheres embolization in the treatment of rupture and bleeding of liver cancer.Method Eighty-five patients with liver cancer of rupture and bleeding who underwent transcatheter arterial embolization(TAE)were divided into gelatin sponge group(n=39)and gelatin sponge combined Embosphere microspheres group(n=46),and the clinical therapeutic effects were compared between the two groups.Result There were no significant differences for the heart rate,systolic blood pressure,diastolic blood pressure(P>0.05)and significant higher hemoglobin(Hb)(P<0.05)in the gelatin sponge combined Embosphere microspheres group than that in the gelatin sponge group after surgery.There were significant lower blood transfusion and rebleeding rate in 7 days in the gelatin sponge combined Embosphere microspheres group than those in the gelatin sponge group(P<0.05).After surgery,glutamic-pyruvic transaminase(ALT),glutamic-oxalacetic transaminase(AST)and total bilirubin(TBil)levels of patients in the gelatin sponge combined Embosphere microspheres group were significantly lower than those in the gelatin sponge group,and albumin(Alb)level were significantly higher than those in the gelatin sponge group(P<0.01).Conclusion The gelatin sponge combined Embosphere microspheres embolization has good clinical effect in the treatment of rupture and bleeding of the liver cancer.
作者
方中平
杨功强
许坤
刘钰
FANG Zhongping;YANG Gongqiang;XU Kun;LIU Yu(Department of Emergency,Xinyang Central Hospital,Xinyang 464031,He’nan,China)
出处
《癌症进展》
2020年第19期2009-2012,共4页
Oncology Progress
