摘要
目的探讨研究SPECT肾动态显像在糖尿病患者早期肾损害中的评估价值。方法方便选取于2019年1—12月到该院进行诊治的100例糖尿病患者为研究对象,根据其尿白蛋白排泄率分为正常白蛋白尿组(49例)、微量白蛋白尿组(23例)、大量白蛋白尿组(28例)3组,对3组患者均行SPECT肾动态显像检测,观察比较3组患者的GFR水平和血生化指标水平。结果①100例患者的白蛋白尿发生率为51.00%(51/100),其中包括微量白蛋白尿23例和大量白蛋白尿28例;②微量白蛋白尿组的GFR水平[(68.57±22.89)mL/min]与正常白蛋白尿组[(75.29±20.72)mL/min]比较差异无统计学意义(t=0.873,P>0.05);大量白蛋白尿组的GFR水平[(64.31±22.12)mL/min]显著低于正常白蛋白尿组(t=2.191,P<0.05);微量白蛋白尿组的GFR水平与大量白蛋白尿组比较差异无统计学意义(t=0.144,P>0.05)。③微量白蛋白尿组的FBG水平显著高于正常白蛋白尿组(t=2.746,P<0.05),BUN、SCr、UA、HbAlc、CH、TG、HDL、LDL水平与正常白蛋白尿组比较均差异无统计学意义(P>0.05);大量白蛋白尿组的BUN、SCr、FBG、CH、LDL水平均显著高于正常白蛋白尿组,差异有统计学意义(P<0.05),UA、HbAlc、TG、HDL水平与正常白蛋白尿组比较差异无统计学意义(P>0.05);微量白蛋白尿组的BUN、SCr、UA、HbAlc、FBG、CH、TG、HDL、LDL水平与大量白蛋白尿组比较差异无统计学意义(P>0.05)。结论SPECT肾动态显像有助于观测糖尿病患者的肾功能情况,是糖尿病早期肾损害的有效诊断手段。
Objective To investigate the value of SPECT renal dynamic imaging in the evaluation of early renal damage in diabetic patients.Methods 100 diabetic patients who came to the hospital for diagnosis and treatment from January to December 2019 were conveniently selected and divided into normal albuminuria group(49 cases)and microalbuminuria group(23 cases),mass albuminuria group(28 cases)according to their urine albumin excretion rate,all 3 groups of patients underwent SPECT renal dynamic imaging to observe and compare the levels of GFR and blood biochemical indicators of the 3 groups.Results 1.The incidence of albuminuria in 100 patients was 51.00%(51/100),including 23 cases of microalbuminuria and 28 cases of macroalbuminuria;2.GFR level of microalbuminuria group[(68.57±22.89)mL/min]Compared with the normal albuminuria group[(75.29±20.72)mL/min],the difference was not statistically significant(t=0.873,P>0.05);the GFR level of the massive albuminuria group[(64.31±22.12)mL/min]was significantly lower than the normal albuminuria group(t=2.191,P<0.05);the GFR level of the microalbuminuria group was not significantly different from that of the macroalbuminuria group(t=0.144,P>0.05).3.The level of FBG in the microalbuminuria group was significantly higher than that of the normal albuminuria group(t=2.746,P<0.05),and the levels of BUN,SCr,UA,HbAlc,CH,TG,HDL and LDL were compared with those in the normal albuminuria group and there was no statistically significant difference(P>0.05);the levels of BUN,SCr,FBG,CH,and LDL in the massive albuminuria group were significantly higher than those in the normal albuminuria group,the difference was statistically significant(P<0.05),and the levels of UA,HbAlc,TG,HDL and there was no statistically significant difference in the normal albuminuria group(P>0.05);there was no statistically significant difference in the levels of BUN,SCr,UA,HbAlc,FBG,CH,TG,HDL,LDL in the microalbuminuria group and the macroalbuminuria group statistically significant(P>0.05).Conclusion SPECT renal dynamic
作者
张世益
ZHANG Shi-yi(Department of Nuclear Medicine,the First Affiliated Hospital of Baotou Medical College,Inner Mongolia University of Science and Technology,Baotou,Inner Mongolia Autonomous Region,014010 China)
出处
《中外医疗》
2020年第27期190-192,共3页
China & Foreign Medical Treatment
