摘要
目的获得辽宁地区中国人的肾脏深度预测方程并对比研究不同肾脏深度算式对辽宁地区中国人的准确性。方法选择2015年11月至2018年1月采用肾动态显像Gates公式测定肾小球滤过率(GFR)并行同机低剂量腹部CT扫描的患者共292例,其中男性220例,女性72例;年龄20~86岁,平均年龄58.02岁。排除有腹水、单肾、肾脏积水、体内或肾内占位病变影响肾脏深度的患者。取肾门水平,测量肾脏前表面、后表面至后背体表皮肤的垂直距离,取其平均值作为肾脏深度。采用多元线性回归逐步向后法分析患者的肾脏深度与性别、年龄、身高、体质量、腹围(AC)、体质量/身高、身高/体质量、体质量指数(BMI)的关系,得出左肾、右肾肾脏深度计算公式。292例患者随机分成2组,一组(175例)得出回归方程,作为生成组,另一组(117例)用于验证方程,作为验证组,并利用χ~2检验及t检验比较两组一般资料的差异。以CT实测值为评价"金标准",将生成组得到的新算式、Tonnesen算式、李乾算式计算的肾脏深度与CT实测值进行单因素方差分析,比较其与CT"金标准"的差异。利用组内相关系数新算式、Tonnesen算式及李乾算式计算的肾脏深度和CT实测值的相关性评价,得到辽宁地区中国人的肾脏深度的准确性较高的算式。结果对肾脏深度有统计学意义的变量是年龄、身高(m)、体质量(kg)和AC(cm),生成组得到的新算式肾脏深度计算公式为:左肾深度(cm)=3.885+0.011×年龄-2.450×身高+0.067×体质量+0.026×AC,右肾深度(cm)=4.474-2.136×身高+0.060×体质量+0.029×AC。结果显示新算式计算的左肾、右肾肾脏深度与CT实测值相比较,左肾、右肾差异均无统计学意义(左肾P=0.544> 0.05,右肾P=0.170> 0.05)。Tonnesen算式、李乾算式计算的肾脏深度相较CT实测值,差异均具有显著统计学意义(P <0.001)。新算式计算的左肾、右肾肾脏深度与CT实测值的相关�
Objective To obtain the renal depth prediction formula of Chinese in Liaoning, and compare accuracy and applicability between Tonnesen formula and Lee formula. Methods From November 2015 to January 2018, a total of 292 patients who detected glomerular filtration rate(GFR) by renal dynamic imaging Gates formula and performed low-dose abdomen CT scanning were enrolled, which included 220 males and 72 females, aged 20-86 years old with mean age of 58.02 years old.Patients with ascites, single kidney, hydronephrosis and lesions in body or kidney that affected depth of kidney were excluded.Taken the horizontal hilum of the kidney, vertical distance between kidney front surface to back skin and kidney back surface to back skin were measured, and mean value was set as kidney depth. The relationship between kidney depth and gender, age,height, body mass, abdominal circumference(AC), body mass/height, height/body mass, and body mass index(BMI) were analyzed by multiple linear regression stepwise backward method, and calculating formula of the left and right kidneys depth was obtained. All of them were randomly divided into 2 groups, one group was used to derive regression equation(n = 175, generating group), and the other group verified equation(n = 117, verification group), and difference of general data between 2 groups was compared using χ~2 test and t test. Taken CT measured value as "gold standard", single factor variance analysis was performed to detected differences of CT measured value with kidney depth calculated by generating group formula, Tonnesen formula or Lee formula. The correlation of coefficients innovation formula, Tonnesen formula and Lee formula were used to calculate correlation between kidney depth and CT measured values, and high accuracy formula of kidney depth of Chinese in Liaoning was obtained. Results The variables statistical significance of kidney depth were age, height(m), weight(kg), and AC(cm), and innovation formula from generation group were as followed: left kidney depth(cm) = 3.885 +
作者
王艳娟
李娜
贾英男
赵爽
宋雪
WANG Yan-juan;LI Na;JIA Ying-nan;ZHAO Shuang;SONG Xue(Department of Nuclear Medicine,the First Hospital of China Medical University,Shenyang 110001,Liaoning,China)
出处
《生物医学工程与临床》
CAS
2020年第5期575-580,共6页
Biomedical Engineering and Clinical Medicine
