摘要
目的:探讨不同年龄段急性心肌梗死(AMI)病人的临床和冠状动脉(冠脉)病变特点。方法:选择201例行急诊冠脉造影检查的AMI病人,根据年龄分为中青年组(<60岁,n=70)和老年组(≥60岁,n=131),比较2组病人的临床资料和冠脉病变资料。结果:AMI老年病人较中青年病人更容易发生院内死亡和心力衰竭(P<0.05);中青年组病人的红细胞计数、血红蛋白、血细胞比容、网织红细胞计数、淋巴细胞计数、嗜酸性粒细胞计数、丙氨酸氨基转移酶、胆碱酯酶、总蛋白、白蛋白、尿酸、总胆固醇、低密度脂蛋白和载脂蛋白B水平均高于老年组(P<0.05~P<0.01),脂蛋白a低于老年组(P<0.05)。中青年组病人冠脉以单支血管病变、低Gensini积分为主,术中发生无/慢复流的概率低;老年组病人冠脉以多支血管、钙化病变、高Gensini积分为主,术中容易出现无/慢复流,2组比较差异有统计学意义(P<0.05~P<0.01)。结论:中青年AMI病人的血压、血糖、血脂水平更高,冠脉病变以单支、低Gesini积分病变为主。老年AMI病人冠脉病变以弥漫性长病变、钙化病变为主,术中容易发生无/慢复流。
Objective:To investigate the clinical and coronary lesion characteristics in different age patients with acute myocardial infarction(AMI).Methods:Two hundred and one AMI patients were detected using emergency coronary angiography,and divided into the young and middle-aged group(age<60 years old,n=70)and elderly group(age≥60 years old,n=131)according to their ages.The clinical data and coronary artery disease data were compared between two groups.Results:Elderly patients with AMI were more prone to have in-hospital death and heart failure compared with young and middle-aged patients(P<0.05).The levels of red blood cell count,hemoglobin,hematocrit,reticulocyte count,lymphocyte count,eosinophil count,alanine aminotransferase,cholinesterase,total protein,albumin,uric acid,total cholesterol,low density lipoprotein and apolipoprotein B in young and middle-aged group were higher than those in elderly group(P<0.05 to P<0.01),and the level of lipoprotein a in young and middle-aged group was lower than that in elderly group(P<0.05).In the young and middle-aged group,the single-vessel lesion and low Gensini score were the main performance,and the probability of no/slow reflow was low.In the elderly group,the coronary arteries were mainly composed of multiple vessels,calcification lesions and high Gensini score,and no/slow reflow was easy to occur during the operation.The difference of which between two groups was statistically significant(P<0.05 to P<0.01).Conclusions:The levels of blood pressure,blood glucose and blood lipid in young and middle-aged patients are higher,and the coronary artery lesions are mainly single-branch and low Gesini score lesions.In the elderly patients,the coronary artery lesions are mainly diffused long lesions and calcificated lesions,and no/slow reflow is easy to occur during the operation.
作者
陈天平
张乃菊
谢彩侠
李妙男
耿旭
胡司淦
刘进军
唐碧
CHEN Tian-ping;ZHANG Nai-ju;XIE Cai-xia;LI Miao-nan;GENG Xu;HU Si-gan;LIU Jin-jun;TANG Bi(Department of Cardiovascular Medicine,The First Affiliated Hospital of Bengbu Medical College,Bengbu Anhui 233004,China;Department of Pharmacy,The First Affiliated Hospital of Bengbu Medical College,Bengbu Anhui 233004,China)
出处
《蚌埠医学院学报》
CAS
2020年第10期1351-1354,共4页
Journal of Bengbu Medical College
基金
蚌埠医学院自然科学研究重点项目(BYKY2019080ZD)
蚌埠医学院自然科学研究项目(Byky1369)。
关键词
急性心肌梗死
中青年
老年
acute myocardial infarction
young and middle-aged
elderly
