摘要
目的系统评价中国大陆成人(≥14岁)哮喘的患病率。方法计算机检索PubMed、Web of Science、CENTRAL、CINAHL、WanFang Data、CBM、CNKI和VIP数据库,搜集有关中国成人哮喘患病率的横断面研究,检索时限均为2000年1月至2019年12月。由2名研究者独立筛选文献、提取数据并评价纳入研究的偏倚风险后,采用Stata 15.0软件进行Meta分析。结果共纳入67个横断面研究,包括1381673例研究对象,19871例成年哮喘患者。Meta分析结果显示,中国成人哮喘患病率为1.81%[95%CI(1.59%,2.01%)]。亚组分析结果显示,中国男、女性哮喘患病率分别为1.87%和1.76%;东北、中部、东部、西部地区哮喘患病率分别为2.16%、1.34%、1.63%、2.23%;15~40岁、41~60岁、>60岁的哮喘患病率分别为0.73%、1.53%、2.81%;文盲、小学、初中、高中、大专及以上哮喘患病率分别为3.07%、1.69%、1.46%、1.01%、0.98%;农林牧业人员、工人、公职人员、商业与服务业人员、军人和其他职业哮喘患病率分别为2.23%、2.10%、1.17%、1.45%、1.09%、1.41%;汉族和其他民族哮喘患病率分别为1.41%、1.59%;城市、农村哮喘患病率分别为2.03%、1.99%;2000~2005年、2006~2010年、2011~2015年、2016~2019年哮喘患病率分别为1.22%、2.07%、2.25%、2.62%。结论中国大陆成人哮喘患病率较高,且研究报道的哮喘患病率有逐年升高的趋势。受年龄、性别、地区、学历和职业的影响,哮喘患病率存在差异。
Objectives To systematically review the prevalence of asthma in adults(>14 years old)in China.Methods PubMed,Web of Science,CENTRAL,CINAHL,WanFang Data,CBM,CNKI,and VIP databases were electronically searched to collect cross-sectional studies on the prevalence of asthma in Chinese adults from January 2000 to December 2019.Two reviewers independently screened literature,extracted data and assessed the risk of bias of included studies,then,meta-analysis was performed by using Stata 15.0 software.Results A total of 67 cross-sectional studies,involving 1381673 subjects and 19871 adult asthma patients were included.The results of meta-analysis showed that the prevalence rate of asthma in adults in China was 1.81%(95%CI 1.59%to 2.01%).The subgroup analysis showed that the prevalence rates of asthma in males and females were 1.87%and 1.76%,respectively.The prevalence rates were 2.16%in the northeast region,1.34%in the central region,1.63%in the eastern region and 2.23%in the western region.The prevalence rates were 0.73%,1.53%,and 2.81%in 15-40 years old,41-60 years old,and>60 years old,respectively.The prevalence rates were 3.07%in illiteracy population,1.69%in primary school population,1.46%in junior middle school population,1.01%in senior high school population and 0.98%in college and above population.The prevalence rates were 2.23%,2.10%,1.17%,1.45%,1.09%,and 1.41%in agriculture,forestry and animal husbandry personnel,workers,public officials,business and service personnel,military personnel,and other occupations,respectively.The prevalence rates were 1.41%and 1.59%in Han and other ethnic populations,respectively.The prevalence rates were 2.03%in cities and 1.99%in rural areas.And the prevalence rates were 1.22%in 2000 to 2005,2.07%in 2006 to 2010,2.25%in 2011 to 2015,and 2.62%in 2016 to 2019.Conclusions The prevalence rate of asthma in Chinese adults is higher,which is different due to the influence of age,sex,region,education,and occupation.
作者
廖小刚
朱爱勇
王欣国
王菲
LIAO Xiaogang;ZHU Aiyong;WANG Xinguo;WANG Fei(Department of Graduate,School of Shanghai University of Traditional Chinese Medicine,Shanghai 201203,P.R.China;Shanghai University of Medicine&Health Sciences,Shanghai 201318,P.R.China;Shanghai University of Traditional Chinese Medicine,Shanghai 201203,P.R.China)
出处
《中国循证医学杂志》
CSCD
北大核心
2020年第10期1164-1172,共9页
Chinese Journal of Evidence-based Medicine
基金
上海市卫健委科研课题(编号:202040381)。
