摘要
目的探讨ANCA不同检测方法对慢性支气管炎患者早期诊断的价值。方法选择我院2019年9月~2020年1月检验科收集的281份血清样本作为研究对象。分别采取线性免疫分析法、间接免疫荧光法和联合检验的方法检测ANCA。结果各种检测方法在ANCA阳性率的检测结果比较,差异无统计学意义(P> 0.05)。对于轻症患者,联合检验的敏感度高于线性免疫分析法和间接免疫荧光法。对于重症患者,联合检验的敏感度高于线性免疫分析法,差异均有统计学意义(P <0.05)。结论联合检验的方法对于早期慢性支气管炎患者具有更为理想的诊断效果。
Objective To explore the significance of different ANCA detection methods for early diagnosis of chronic bronchitis in the patients.Methods From September 2019 to January 2020,281 serum samples collected by the Department of Clinical Laboratory of our hospital were selected as the subjects of research.Linear immunoassay,indirect immunofluorescence and combined test were respectively used to detect ANCA.Results There was no statistically significant difference in the result of ANCA positive rate among the detection methods(P>0.05).For patients with mild diseases,the sensitivity of the combined test were higher than those of linear immunoassay and indirect immunofluorescence.For critically ill patients,the sensitivity of the combined test was higher than that of linear immunoassay,and the difference was statistically significant(P<0.05).Conclusion The combined test method has a more satisfying diagnostic effect on patients with early chronic bronchitis.
作者
于红博
王海波
YU Hongbo;WANG Haibo(Department of Clinical Laboratory,Jilin Central General Hospital,Jilin,Jilin 132000,China;Department of Clinical Laboratory,the Affiliated Hospital of Jilin Medical Univesity,Jilin,Jilin 132013,China)
出处
《中国医药科学》
2020年第17期169-172,共4页
China Medicine And Pharmacy
基金
吉林省吉林市医疗卫生计划项目(2019001023)。