摘要
目的:观察防栓方预防妇科盆腔手术后深静脉血栓(deep vein thrombosis,DVT)形成的效果。方法:选取我院2016年1月至2017年1月间收治的60例妇科良性疾病且需行盆腔手术的患者作为研究对象,随机将其分为试验组和对照组,每组各30例。试验组于术后即进行双下肢按摩并口服防栓方。对照组术后仅行双下肢按摩。对比两组患者手术前、术后第3 d与术后第7 d的D-二聚体、血浆和全血粘度、红细胞聚集指数、双下肢血管彩超及深静脉血栓发生率。结果:对照组于术后第3 d与手术前相比,D-二聚体、血浆和全血粘度指标都有较明显升高(P<0.05);对照组术后第7 d血浆和全血粘度值明显低于术后第3 d,差异均具有统计学意义(P<0.05);术后第3 d和第7 d,试验组患者D-二聚体、血浆和全血粘度指标均明显较对照组低,差异均具有统计学差异(P<0.05);比较两组DVT发生率,差异无统计学意义(P>0.05)。结论:防栓方可通过改善患者血流速度,调节术后患者血液高凝及高粘状态,从而抑制血管内血栓形成,有效减少妇科盆腔手术后DVT事件的发生。
Objective:To observe the efficacy of Fangshuan Prescription in prevention of lower extremity deep venous thrombosis(DVT)after gynecological pelvic surgery.Methods:Sixty patients who were admitted to our hospital for benign gynecological diseases and underwent pelvic surgery from January 2016 to January 2017 were enrolled as subjects and randomly and equally divided into experimental group and control group.The experimental group received lower extremity massage and oral administration of Fangshuan Prescription immediately after surgery,while the control group only received lower extremity massage after surgery.The plasma D-dimer level,plasma and whole blood viscosity indices,erythrocyte aggregation index,Doppler ultrasound of lower limbs,and incidence of DVT were compared between the two groups before surgery and at 3 and 7 days after surgery.Results:In the control group,the D-dimer level and plasma and whole blood viscosity indices were significantly higher at 3 days after surgery than before surgery(P<0.05);the plasma and whole blood viscosity indices were significantly higher at 7 days after surgery than at 3 days after surgery(P<0.05).At 3 and 7 days after surgery,the experimental group had significantly lower D-dimer level and plasma and whole blood viscosity indices than the control group(P<0.05).There was no significant difference in the incidence of DVT between the two groups(P>0.05).Conclusion:Fangshuan Prescription can inhibit thrombosis and substantially reduce the incidence of DVT after gynecological pelvic surgery by improving blood flow velocity and regulating high blood coagulation and high viscosity.
作者
林光耀
万小林
聂红
吴敏
王永周
LIN Guangyao;WAN Xiaolin;NIE Hong;WU Min;WANG Yongzhou(Department of Aynecology and Obsterice,the Affiliated TCM Hospital of Southwest Medical University,Luzhou 646000,Sichuan Province,China)
出处
《西南医科大学学报》
2020年第5期483-486,共4页
Journal of Southwest Medical University
基金
四川省中医药管理局项目(项目编号2018YY010)。
关键词
防栓方
妇科盆腔手术后
下肢深静脉血栓
临床观察
Fangshuan Prescription
After gynecological pelvic surgery
Lower extremity deep venous thrombosis
Clinical observation
