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活血利水汤治疗四肢骨折术后肿胀的疗效观察及有效性评价 被引量:2

Efficacy of the Huoxue Lishui decoction on swelling after limb fracture
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摘要 目的:探讨四肢骨折术后并发肿胀的患者取中药活血利水汤方案治疗效果.方法:对四肢骨折术后并发肿胀的100例患者予以选取,均为我院骨科2017年5月-2019年5月收治,应用数字表抽取法随机分组,就应用常规甘露醇注射液静滴方案治疗(对照组,50例)与加用中药活血利水汤方案治疗(观察组,50例)效果、治疗后不同时点疼痛及肿胀程度、治疗前后血浆粘度指标及炎性因子指标水平、并发症率展开对比.结果:观察组四肢骨折术后肿胀患者总有效率高于对照组(P<0.05).两组治疗后3 d、5 d疼痛评分、肿胀程度经测验均低于对照组(P<0.05).两组治疗前,血浆粘度指标经测验无差异(P>0.05),治疗后,测验值相较治疗前均有降低,且观察组降低程度较对照组更为显著(P<0.05).两组治疗前,炎性因子即肿瘤坏死因子-α(Tumor Necrosis Factor alpha,TNF-α)、白细胞介素-1(Interleukin-1,IL-1)、白细胞介素-6(Interleukin-6,IL-6)指标水平经测验差异无统计学意义(P>0.05),治疗后各指标测验值均有降低,且相较对照组,观察组下降程度较对照组更为显著(P<0.05).观察组并发症率低于对照组(P<0.05).结论:四肢骨折术后并发肿胀的患者应用活血利水汤予以治疗,可提高临床效果,缓解疼痛及肿胀程度,降低血浆粘度,消除炎性反应,且具更高安全性,临床应用价值突出. Objective:To investigate clinical efficacy of the Huoxue Lishui decoction(活血利水汤)on swelling after limb fracture.Methods:100 cases were divided into 2 groups,50 cases in each.The control group was given the mannitol injection,and the observation group was given the Huoxue Lishui decoction more.Results:The total efficiency in the observation group was higher than the control group(P<0.05).In 3 days and 5 days,the pain score and swelling degree in the observation group were lower than the control group(P<0.05).After treatment,the plasma viscosity in both groups were decreased,and the reduction in the observation group was more significant(P<0.05).After treatment,the levels of TNF-α,IL-1 and IL-6 were decreased in both groups,and the decrease in the observation group was more significant(P<0.05).The complication rate in the observation group was lower than the control group(P<0.05).Conclusion:The Huoxue Lishui decoction on swelling after limb fracture shows good effects,can improve the degree of pain relief and swelling,reduce plasma viscosity,eliminate inflammatory reactions,and have higher safety.
作者 杜保奇 Du Baoqi
出处 《中医临床研究》 2020年第20期70-72,共3页 Clinical Journal Of Chinese Medicine
关键词 骨折 活血利水汤 肿胀 疼痛 血浆粘度 炎性因子水平 Fracture The Huoxue Lishui decoction Swelling Pain Plasma viscosity Inflammatory factor level
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