摘要
目的了解德州市手足口病流行特征及其分布特征,为制定手足口病防控措施提供参考依据。方法对德州市2008~2018年手足口病疫情资料进行描述性流行病学分析。结果2008~2018年德州市共报告发病49641例,年均发病率为79.78/10万,对发病率做趋势性χ2检验,差异有统计学意义(P<0.01);每年手足口病发病主要为1个夏季发病高峰,第2个秋季发病小高峰不明显,表现为下降趋势受阻并略有上升;德州市各县市区报告发病略有不同,2008~2018年手足口病报告发病数居前5位的县市区为德城区(9241例)、夏津县(5200例)、宁津县(5101例)、乐陵市(5069例)、临邑县(4886例),不同年份不同地区有不同程度的变动;5岁及以下的儿童发病较多,男孩(31185例)多于女孩(18456例)(P<0.01);病原学分布呈现引起手足口病的不同型别肠道病毒交替流行,大致每3年1个流行周期,每年确诊病例中感染EV 71的病例所占比例逐月下降,感染Cox A16的病例在每个季度所占比例稳定于20%~25%,感染其他肠道病毒的病例所占比例呈现逐月上升的趋势。结论德州市手足口病疫情呈现大致呈每隔2年高发的特征,不同型别肠道病毒交替流行,以5岁及以下散居儿童为主,5~8月为高发月份。
Objective To understand the epidemiological and distribution characteristics of hand,foot,and mouth disease(HFMD)in Dezhou city during 2008-2018,so as to provide the reference for developing prevention and control measures of HFMD.Methods Descriptive epidemiological method was used to analyze HFMD epidemiological data in Dezhou city during 2008-2018.Results A total of 49641cases were reported during 2008-2018,with an average annual incidence of 79.78/105.The trend ofχ2 test was observed in the past 11years.The difference of individual annual incidence was statistically significant(P<0.01).The incidence of HFMD was mainly a summer incidence peak,the second autumn incidence peak was not obvious,the performance showed that the downward trend was blocked and slightly increased;the counties in Dezhou city reported a slightly different incidence of HFMD in 2008-2018.The counties with the highest number of reported cases were Decheng district(9241),Xiajin county(5200),Ningjin county(5101),Laoling city(5069),and Linyi county(4886).There were different degrees of change in different years and different areas;children aged 5years and younger had more epidemics.Boys(31185)had more cases than girls(18456)(P<0.01);the etiology distribution showed alternating epidemics of different types of enteroviruses causing HFMD,roughly every 3years was 1epidemic cycle.Among the confirmed cases per year,the proportion of cases infected with EV 71decreased month by month,and the proportion of cases infected with Cox A16was stable at 20%-25%in each quarter,and the proportion of cases infected with other enterovirus showed a monthly increase.Conclusion The outbreak of HFMD in Dezhou city is characterized by high incidence every 2years.Different types of enteroviruses alternate in prevalence,cases concentrate in scattered children aged 5years and younger,and peak in May-August.
作者
魏新梅
杨卫红
王壮业
王冬梅
崔永彪
WEI Xin-mei;YANG Wei-hong;WANG Zhuang-ye;WANG Dong-mei;CUI Yong-biao(Dezhou City Center for Disease Control and Prevention,Dezhou,Shandong,253016,China;不详)
出处
《预防医学论坛》
2020年第8期602-605,610,共5页
Preventive Medicine Tribune
关键词
手足口病
流行特征
肠道病毒
Hand,foot,and mouth disease
Epidemiological characteristics
Enterovirus
